PETCT与CT灌注成像在脑肿瘤患者分型与分级中的诊断价值研究
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摘要
目的:研究PETCT与CT灌注成像在脑肿瘤患者分型与分级中的诊断价值。方法:选取于本院进行诊治的75例脑肿瘤患者为研究对象,将其以PETCT进行扫描,然后以CT灌注成像进行检查,然后将其中不同分型患者的检测结果进行比较,并比较脑胶质瘤患者中不同分级及脑转移瘤中不同分型者的检测结果。结果:脑膜瘤患者的CBF、CBV及PS均高于胶质瘤及转移瘤,MTT则短于脑胶质瘤及转移瘤,脑胶质瘤及转移瘤患者SUV值及SUVmax阳性率均高于脑膜瘤患者,而脑胶质瘤患者中分级较高者的CBF、CBV、PS、SUV值及SUVmax阳性率均高于分级较低者,MTT则短于分级较低者,差异均具有统计学意义(P<0.05),而脑转移瘤患者中不同分型者的上述指标比较,差异均无统计学意义(P>0.05)。结论:PETCT与CT灌注成像在脑肿瘤患者分型与分级中的诊断价值较高,临床应用价值较高。
Objective:To investigate the value of PETCT and CT perfusion imaging in diagnosis of different types and classifications of patients with cerebral tumor.Methods:A total of 75 patients with cerebral tumor treated in our hospital were selected as the research object,and all the patients underwent PETCT scan and CT perfusion imaging detection,then the detection results regarding to different types and different classifications of brain glioma and different types of metastatic encephaloma were compared between the two groups.Results:The CBF,CBV and PS of patients with meningiomas were all higher than those of patients with brain glioma and metastatic encephaloma,the MTT were shorter than those of patients with brain glioma and metastatic encephaloma.The positive rates of SUV value and SUVmax patients with brain glioma and metastatic encephaloma were higher than those of patients with meningiomas,while the positive rate of CBF,CBV,PS,SUV value and SUVmax patients with higher classifications of brain glioma were all higher than those of patients with lower classifications of brain glioma,the MTT were shorter than those of patients with lower classifications of brain glioma(Pall< 0.05),but those indexes of patients with different types of metastatic encephaloma were not significantly different from each other(Pall>0.05).Conclusion:The value of PETCT and CT perfusion imaging in diagnosis of different types and classifications of cerebral tumor are high.
Objective:To investigate the value of PETCT and CT perfusion imaging in diagnosis of different types and classifications of patients with cerebral tumor.Methods:A total of 75 patients with cerebral tumor treated in our hospital were selected as the research object,and all the patients underwent PETCT scan and CT perfusion imaging detection,then the detection results regarding to different types and different classifications of brain glioma and different types of metastatic encephaloma were compared between the two groups.Results:The CBF,CBV and PS of patients with meningiomas were all higher than those of patients with brain glioma and metastatic encephaloma,the MTT were shorter than those of patients with brain glioma and metastatic encephaloma.The positive rates of SUV value and SUVmax patients with brain glioma and metastatic encephaloma were higher than those of patients with meningiomas,while the positive rate of CBF,CBV,PS,SUV value and SUVmax patients with higher classifications of brain glioma were all higher than those of patients with lower classifications of brain glioma,the MTT were shorter than those of patients with lower classifications of brain glioma(Pall< 0.05),but those indexes of patients with different types of metastatic encephaloma were not significantly different from each other(Pall>0.05).Conclusion:The value of PETCT and CT perfusion imaging in diagnosis of different types and classifications of cerebral tumor are high.
引文
1李玲玲.多层螺旋ct灌注成像在脑胶质瘤分级中的临床应用价值[J].当代医学,2014,20(29):17-18.
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3 全冠民,赵宁,袁涛,等.ct灌注对表现为局限性低密度的脑肿瘤与非肿瘤性病变的鉴别诊断[J].放射学实践,2013,28(5):522-527.
4 胡步宏,任广,耿道颖.脑膜瘤瘤周水肿的64层螺旋ct灌注成像定量研究[J].中国医学计算机成像杂志,2012,18(2):97-101.
5 Argyro Xyda,Ulrike Haberland,Ernst Klotz,et al.Brain volume perfusion CT performed with 128-detector row CT system in patients with cerebral gliomas:A feasibility study[J].Eur Radiol,2011,21(9):1811-1819.
6 Barbara Palumbo,Tommaso Buresta,Susanna Nuvoli,et al.SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases[J].Int J Mol Sci,2014,15(6):9878-9893.
7 于雷,王莹莹,胡祥华,等.11C-MET pet/ct在高级别脑胶质瘤适形放疗方案制定中的价值[J].中华核医学与分子影像杂志,2015,35(2):102-107.
8 周克迪,王贺宁,李素莹,等.pet/ct脑成像新药研究发展趋势及基于pet/ct设备的脑成像新药研发[J].中国医疗设备,2015,30(4):11-14.
9 余日胜,陈璐.脑肿瘤影像诊断技术新进展[J].现代实用医学,2015,27(5):557-559.
10 陈维娟,陈婷,郭大静,等.全脑ct灌注成像在邻近大血管颅内肿瘤中的临床应用[J].激光杂志,2014,35(5):81-84.
2 房娜,王艳丽,曾磊,等.18F-FDG pet/ct显像在颅内占位性病变诊断中的价值[J].齐鲁医学杂志,2014,29(1):15-18.
3 全冠民,赵宁,袁涛,等.ct灌注对表现为局限性低密度的脑肿瘤与非肿瘤性病变的鉴别诊断[J].放射学实践,2013,28(5):522-527.
4 胡步宏,任广,耿道颖.脑膜瘤瘤周水肿的64层螺旋ct灌注成像定量研究[J].中国医学计算机成像杂志,2012,18(2):97-101.
5 Argyro Xyda,Ulrike Haberland,Ernst Klotz,et al.Brain volume perfusion CT performed with 128-detector row CT system in patients with cerebral gliomas:A feasibility study[J].Eur Radiol,2011,21(9):1811-1819.
6 Barbara Palumbo,Tommaso Buresta,Susanna Nuvoli,et al.SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases[J].Int J Mol Sci,2014,15(6):9878-9893.
7 于雷,王莹莹,胡祥华,等.11C-MET pet/ct在高级别脑胶质瘤适形放疗方案制定中的价值[J].中华核医学与分子影像杂志,2015,35(2):102-107.
8 周克迪,王贺宁,李素莹,等.pet/ct脑成像新药研究发展趋势及基于pet/ct设备的脑成像新药研发[J].中国医疗设备,2015,30(4):11-14.
9 余日胜,陈璐.脑肿瘤影像诊断技术新进展[J].现代实用医学,2015,27(5):557-559.
10 陈维娟,陈婷,郭大静,等.全脑ct灌注成像在邻近大血管颅内肿瘤中的临床应用[J].激光杂志,2014,35(5):81-84.