脉冲CO_2点阵激光结合E光治疗痤疮瘢痕疗效分析
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摘要
目的:探究脉冲CO_2点阵激光结合E光治疗痤疮瘢痕的疗效。方法:选取2012年3月-2016年9月笔者医院进行面部瘢痕整复患者104例,将所有患者随机分为研究组和对照组,其中对照组使用脉冲激光对面部瘢痕进行修复,研究组使用脉冲CO_2点阵激光结合E光的方法进行治疗。对两组患者治疗后临床效果、结痂时间、疼痛持续时间、不良反应发生率、视觉模拟评分(VAS评分)及满意度进行比较。结果:研究组治疗有效率显著优于对照组,差异有统计学意义(P<0.05);研究组结痂时间、疼痛持续时间、视觉模拟评分(VAS评分)及不良反应发生率均低于对照组,差异有统计学意义(P<0.05);研究组患者治疗满意度显著高于对照组(P<0.05)。结论:脉冲CO_2点阵激光结合E光治疗面部瘢痕效果显著,能有效提高治疗满意度,明显降低患者疼痛率与不良反应发生率,值得在临床中推广使用。
Objective To explore the effect of pulsed CO_2 lattice laser combined with E-ray on acne scar. Methods 104 patients who underwent facial scar repair in our hospital from March 2012 to September 2016 were selected. All patients were randomly divided into study group and control group. The control group used pulsed laser to repair facial scar, while the study group used pulsed CO_2 lattice laser combined with E-ray to treat facial scar. The clinical effect, scab formation time, pain duration,incidence of adverse reactions, visual analogue scale(VAS) and satisfaction were compared between the two groups. Results The treatment efficiency of the study group patients was significantly better than that of the control group(P<0.05). The team with scab oer time, pain duration, visual analogue scale(VAS score) and the incidence of adverse reactions were significantly lower than control group(P<0.05), the satisfaction of patients in study group was significantly higher than that in control group(P<0.05). Conclusion In the clinical treatment of patients with facial scar repair, pulsed CO_2 lattice laser combined with E light has a significant effect, and the pain rate and the incidence of adverse reactions of patients are significantly reduced, so the effective improvement of patients' satisfaction should be promoted in clinical treatment.
Objective To explore the effect of pulsed CO_2 lattice laser combined with E-ray on acne scar. Methods 104 patients who underwent facial scar repair in our hospital from March 2012 to September 2016 were selected. All patients were randomly divided into study group and control group. The control group used pulsed laser to repair facial scar, while the study group used pulsed CO_2 lattice laser combined with E-ray to treat facial scar. The clinical effect, scab formation time, pain duration,incidence of adverse reactions, visual analogue scale(VAS) and satisfaction were compared between the two groups. Results The treatment efficiency of the study group patients was significantly better than that of the control group(P<0.05). The team with scab oer time, pain duration, visual analogue scale(VAS score) and the incidence of adverse reactions were significantly lower than control group(P<0.05), the satisfaction of patients in study group was significantly higher than that in control group(P<0.05). Conclusion In the clinical treatment of patients with facial scar repair, pulsed CO_2 lattice laser combined with E light has a significant effect, and the pain rate and the incidence of adverse reactions of patients are significantly reduced, so the effective improvement of patients' satisfaction should be promoted in clinical treatment.
引文
[1]姜嵩,张艺琼,陈媛,等.超脉冲CO2点阵激光联合针刺疗法治疗痤疮凹陷性瘢痕的自身对照观察[J].中国皮肤性病学杂志,2017,31(8):912-915.
[2]吴树毅,何仁亮,李凤春.二氧化碳点阵激光联合异维A酸治疗炎性痤疮的疗效观察[J].广东医学,2018,39(16):73-77.
[3]Ochi H,Tan L,Tan W P,et al.Treatment of facial acne scarring with fractional carbon dioxide laser in asians,a retrospective analysis of efficacy and complications[J].Dermatol Surg,2017,43(9):1137-1143.
[4]王忱,韩晓锋,徐子刚,等.超脉冲CO2点阵激光治疗儿童汗孔角化症九例[J].中华皮肤科杂志,2017,50(11):844-846.
[5]雷颖,李石峰,喻亿玲,等.不同超脉冲二氧化碳点阵激光模式联合治疗面颈部增生性瘢痕的临床效果[J].中华烧伤杂志,2016,32(8):474-478.
[6]李娜,杨丽,程静,等.脉冲染料激光与超脉冲点阵二氧化碳激光治疗烧伤后增生性瘢痕的临床对比研究[J].中华烧伤杂志,2018,34(9):603-607.
[7]Yordanov YP,Shef A.Lower eyelid reconstruction after ablation of skin malignancies:how far can we get in a single-stage procedure?[J].J Craniofac Surg,2017,28(5):e477.
[8]詹明峰,尚佩生,孙士芳,等.点阵CO2激光局灶性照射与平扫照射治疗面部痤疮萎缩性瘢痕效果比较[J].山东医药,2018,23(2):95-98.
[9]Phothong W,Wanitphakdeedecha R,Sathaworawong A,et al.High versus moderate energy use of bipolar fractional radiofrequency in the treatment of acne scars:a split-face double-blinded randomized control trial pilot study[J].Lasers Med Sci,2016,31(2):229-234.
[10]康小平,董明国,龙飞,等.超脉冲二氧化碳点阵激光治疗对女性凹陷性痤疮瘢痕患者p38MAPK通路蛋白的影响[J].广东医学,2016,37(22):3397-3399.
[11]刘秀峰,潘文东,张元文,等.点阵激光联合复方倍他米松注射液治疗增生性瘢痕20例疗效观察[J].中国皮肤性病学杂志,2016,30(5):527-529.
[12]Wei J,Herrler T,Xu H,et al.Double composite tissue z-plasty technique for anatomical restoration of severe nasal deformity in secondary unilateral cleft lip[J].Ann Plast Surg,2017,79(4):359.
[13]赵翠杨,夏丹英,马蕾.rh EGF联合点阵激光对痤疮疤痕患者皮肤屏障功能及TLR2水平的影响[J].中国现代医学杂志,2017,27(28):110-114.
[14]张娜,金岚,李任.非剥脱性StarluxTM 1 540点阵激光与强脉冲光治疗面部毛孔粗大的临床疗效比较[J].激光杂志,2018,19(1):159-163.
[15]Suh YC,Choi JW,Oh TS,et al.Analysis of extended transconjunctival approach with lateral paracanthal incision:a study among classical methods of orbital approach and new method[J].J Craniofac Surg,2016,27(8):2050-2054.
[2]吴树毅,何仁亮,李凤春.二氧化碳点阵激光联合异维A酸治疗炎性痤疮的疗效观察[J].广东医学,2018,39(16):73-77.
[3]Ochi H,Tan L,Tan W P,et al.Treatment of facial acne scarring with fractional carbon dioxide laser in asians,a retrospective analysis of efficacy and complications[J].Dermatol Surg,2017,43(9):1137-1143.
[4]王忱,韩晓锋,徐子刚,等.超脉冲CO2点阵激光治疗儿童汗孔角化症九例[J].中华皮肤科杂志,2017,50(11):844-846.
[5]雷颖,李石峰,喻亿玲,等.不同超脉冲二氧化碳点阵激光模式联合治疗面颈部增生性瘢痕的临床效果[J].中华烧伤杂志,2016,32(8):474-478.
[6]李娜,杨丽,程静,等.脉冲染料激光与超脉冲点阵二氧化碳激光治疗烧伤后增生性瘢痕的临床对比研究[J].中华烧伤杂志,2018,34(9):603-607.
[7]Yordanov YP,Shef A.Lower eyelid reconstruction after ablation of skin malignancies:how far can we get in a single-stage procedure?[J].J Craniofac Surg,2017,28(5):e477.
[8]詹明峰,尚佩生,孙士芳,等.点阵CO2激光局灶性照射与平扫照射治疗面部痤疮萎缩性瘢痕效果比较[J].山东医药,2018,23(2):95-98.
[9]Phothong W,Wanitphakdeedecha R,Sathaworawong A,et al.High versus moderate energy use of bipolar fractional radiofrequency in the treatment of acne scars:a split-face double-blinded randomized control trial pilot study[J].Lasers Med Sci,2016,31(2):229-234.
[10]康小平,董明国,龙飞,等.超脉冲二氧化碳点阵激光治疗对女性凹陷性痤疮瘢痕患者p38MAPK通路蛋白的影响[J].广东医学,2016,37(22):3397-3399.
[11]刘秀峰,潘文东,张元文,等.点阵激光联合复方倍他米松注射液治疗增生性瘢痕20例疗效观察[J].中国皮肤性病学杂志,2016,30(5):527-529.
[12]Wei J,Herrler T,Xu H,et al.Double composite tissue z-plasty technique for anatomical restoration of severe nasal deformity in secondary unilateral cleft lip[J].Ann Plast Surg,2017,79(4):359.
[13]赵翠杨,夏丹英,马蕾.rh EGF联合点阵激光对痤疮疤痕患者皮肤屏障功能及TLR2水平的影响[J].中国现代医学杂志,2017,27(28):110-114.
[14]张娜,金岚,李任.非剥脱性StarluxTM 1 540点阵激光与强脉冲光治疗面部毛孔粗大的临床疗效比较[J].激光杂志,2018,19(1):159-163.
[15]Suh YC,Choi JW,Oh TS,et al.Analysis of extended transconjunctival approach with lateral paracanthal incision:a study among classical methods of orbital approach and new method[J].J Craniofac Surg,2016,27(8):2050-2054.