强脉冲光联合自身血液浓缩生长因子防治面部皮肤老化的临床观察
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摘要
目的观察强脉冲光联合自身CGF(Concentrate Growth Factors)防治面部皮肤老化的疗效及安全性。方法 90例健康女性,随机分为3组,每组30例,其分别为单纯强脉冲光,单纯CGF组,强脉冲光联合CGF组。三组的治疗频次相同,每月一次,6次为1疗程。12个月后观察疗效。结果强脉冲光加CGF组有效率92.6%明显高于单纯强脉冲光66.6%,单纯CGF组70%,差异显著,(P <0.05),统计学意义。结论强脉冲光联合CGF防治皮肤老化有显著疗效,优于单纯强脉冲光和单纯CGF,值得临床推广。
Objective To observe the efficacy and safety of intense pulse light combined with self-CGF(Concentrate Growth Factors) in the prevention and treatment of facial skin aging. Methods 90 healthy women were randomly divided into 3 groups(30 cases in each group): single intense pulse light, simple CGF group, strong pulse light combined with CGF group. The treatment frequency of the three groups was the same, once a month, 6 times as a course of treatment. 12 months later, the curative effect was observed. Results The effective rate of intense pulse light plus CGF group was 92.6% higher than that of CGF group(66.6%) and CGF group(70%), the difference was significant(P < 0.05). Significant,(P < 0.05, statistically significant. Conclusion Intense pulse light combined with CGF is effective in the prevention and treatment of skin aging. It is better than strong pulse light and CGF, alone in the prevention and treatment of skin aging.
Objective To observe the efficacy and safety of intense pulse light combined with self-CGF(Concentrate Growth Factors) in the prevention and treatment of facial skin aging. Methods 90 healthy women were randomly divided into 3 groups(30 cases in each group): single intense pulse light, simple CGF group, strong pulse light combined with CGF group. The treatment frequency of the three groups was the same, once a month, 6 times as a course of treatment. 12 months later, the curative effect was observed. Results The effective rate of intense pulse light plus CGF group was 92.6% higher than that of CGF group(66.6%) and CGF group(70%), the difference was significant(P < 0.05). Significant,(P < 0.05, statistically significant. Conclusion Intense pulse light combined with CGF is effective in the prevention and treatment of skin aging. It is better than strong pulse light and CGF, alone in the prevention and treatment of skin aging.
引文
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[6]Eckert RL,Crish JF,Eobinson NA.The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation[J].Physiol Rey,1997,77(2):397-424.
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[9]高景恒,白怜珉,李孟倩.强脉冲光在美容外科应用的文献复习[J].实用美容整形外科杂志,2003,14(1):39-43.doi:10.3969/j.issn.1673-7040.2003.01.018
[10]顾伟康,任秋实,李万荣.强脉冲光子美容技术的回顾与进展[J].激光生物学报,2004,13(6):455-460.doi:10.3969/j.issn.1007-7146.2004.06.013
[11]Huang Z,Zhou D,Ren QS.Biomechanical properties and Modeling of skin with Laser infuence[J].J Shanghai Jiaotong University,2001,16(5):610-631.
[12]岳丹霞,刘丽红,樊昕,等,强脉冲光治疗光老化的皮肤测试与评价[J].中国美容医学,2011,20(8):1279-1280.doi:10.3969/j.issn.1008-6455.2011.08.040
[13]刘耿,王永贤,邹芥.新型强脉冲光对面部皮肤美白作用的研究[J].中国美容医学,2009,18(4):517-520从而达到防治面部皮肤老化的作用.doi:10.3969/j.issn.1008-6455.2009.04.033
[14]Sutherland J,Denyer M,Britland S,et a1.Motogenic substrataand chemokinetic growth factors for human skin cells.J Anat,2005,207(1):67-78.
[2]Dierickx CC,Anderson RR.Visible light treatment of photoaging[J].Dermatol Ther,2005,18:191-208.DOI:10.1111/j.1529-8019.2005.05019.x
[3]Friedman DJ,Gilend LT.The use of hybrid radiofrequency device for the treatment of rhytides and lax skin[J].Dermatol Surg,2007,33(5):543-551.doi:10.1111/j.1524-4725.2007.33112.x
[4]Zelickson BD,Kist D,Bemstein E,et al.Histological and ultrastructural evaluation of the effects of a radiofrequency based nonablative dermal remodeling device:a pilot study[J].Arch Dermatol,2004,140(2):204-209.doi:10.1001/archderm.140.2.204
[5]Aster TS,Tanzi E.Improvement of neck and check laxity with a nonablative radiofreauqency device:a lifting experience[J].Dermatol Surg,2004,30(4ptl):503-507.
[6]Eckert RL,Crish JF,Eobinson NA.The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation[J].Physiol Rey,1997,77(2):397-424.
[7]Griffiths CFM,Drug treatment of photoaged skin[J].Drug Aging,1999,14(4):289-301.
[8]王红丽,吴铁.皮肤衰老分子生物学机制的研究进展[J].国外医学.皮肤性病学分册,2003,29(2):114-116.DOI:10.3760/cma.j.issn.1673-4173.2003.02.016
[9]高景恒,白怜珉,李孟倩.强脉冲光在美容外科应用的文献复习[J].实用美容整形外科杂志,2003,14(1):39-43.doi:10.3969/j.issn.1673-7040.2003.01.018
[10]顾伟康,任秋实,李万荣.强脉冲光子美容技术的回顾与进展[J].激光生物学报,2004,13(6):455-460.doi:10.3969/j.issn.1007-7146.2004.06.013
[11]Huang Z,Zhou D,Ren QS.Biomechanical properties and Modeling of skin with Laser infuence[J].J Shanghai Jiaotong University,2001,16(5):610-631.
[12]岳丹霞,刘丽红,樊昕,等,强脉冲光治疗光老化的皮肤测试与评价[J].中国美容医学,2011,20(8):1279-1280.doi:10.3969/j.issn.1008-6455.2011.08.040
[13]刘耿,王永贤,邹芥.新型强脉冲光对面部皮肤美白作用的研究[J].中国美容医学,2009,18(4):517-520从而达到防治面部皮肤老化的作用.doi:10.3969/j.issn.1008-6455.2009.04.033
[14]Sutherland J,Denyer M,Britland S,et a1.Motogenic substrataand chemokinetic growth factors for human skin cells.J Anat,2005,207(1):67-78.