腹部手术患者应用不同剂量右美托咪定复合麻醉的观察
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摘要
目的观察腹部手术患者麻醉中应用不同剂量右美托咪定复合异丙酚、瑞芬太尼的麻醉效果。方法随机将80例腹部手术患者分为研究组、对照组各40例,两组均给予右美托咪定复合异丙酚、瑞芬太尼麻醉,对照组右美托咪定剂量为0.5μg/kg,研究组右美托咪定剂量为0.8μg/kg。记录两组患者平均拔管时间、瑞芬太尼使用量、异丙酚使用量、苏醒时间、不良反应发生率。结果研究组患者的平均拔管时间、异丙酚使用量、苏醒时间、瑞芬太尼使用量、不良反应发生率均低于对照组,差异有统计学意义(P <0.05)。结论在腹部手术患者麻醉过程中,0.8μg/kg右美托咪定复合异丙酚、瑞芬太尼的麻醉好,可以减少瑞芬太尼和异丙酚使用量,患者苏醒时间短、不良反应少,麻醉效果安全可靠。
Objective To observe the anesthetic effect of dexmedetomidine combined with propofol and remifentanil appling in anesthesia for abdominal surgery patients. Methods 80 cases of abdominal surgery patients were randomly divided into the study group(n=40) and the control group(n=40). The two groups were anesthetized with dexmedetomidine combined with propofol and remifentanil. The dose of dexmedetomidine in the control group was 0.5 μg/kg, and the dose of dexmedetomidine in the study group was 0.8μg/kg. The mean extubation time, remifentanil usage, propofol usage, the waking time and adverse reaction rate of the two groups were recorded. Results The mean extubation time, the usage of propofol, the waking time, the dosage of remifentanil and the incidence of adverse reactions in the study group were significantly lower than the control group, the difference is statistically significant(P < 0.05). Conclusion During anesthesia in patients undergoing abdominal surgery, the anesthesia effects of dexmedetomidine 0.8μg/kg combined with propofol and remifentanil is good, it can reduce the dosage of remifentanil and propofol, the recovery time is short, and has less adverse reactions, the anesthetic effect is safety and reliable.
Objective To observe the anesthetic effect of dexmedetomidine combined with propofol and remifentanil appling in anesthesia for abdominal surgery patients. Methods 80 cases of abdominal surgery patients were randomly divided into the study group(n=40) and the control group(n=40). The two groups were anesthetized with dexmedetomidine combined with propofol and remifentanil. The dose of dexmedetomidine in the control group was 0.5 μg/kg, and the dose of dexmedetomidine in the study group was 0.8μg/kg. The mean extubation time, remifentanil usage, propofol usage, the waking time and adverse reaction rate of the two groups were recorded. Results The mean extubation time, the usage of propofol, the waking time, the dosage of remifentanil and the incidence of adverse reactions in the study group were significantly lower than the control group, the difference is statistically significant(P < 0.05). Conclusion During anesthesia in patients undergoing abdominal surgery, the anesthesia effects of dexmedetomidine 0.8μg/kg combined with propofol and remifentanil is good, it can reduce the dosage of remifentanil and propofol, the recovery time is short, and has less adverse reactions, the anesthetic effect is safety and reliable.
引文
[1]杨海峰,瞿玉莲.不同剂量右美托咪啶复合异丙酚和瑞芬太尼用于腹部手术患者麻醉的效果[J].中国生化药物杂志,2017,37(8):133-134.
[2]田立东,张麟临,刘继强,等.布托啡诺复合右美托咪定对瑞芬太尼诱发术后痛觉过敏的影响[J].中华麻醉学杂志,2015,35(4):401-404.
[3]郑雪琴,车晓琪.右美托咪定复合丙泊酚和瑞芬太尼用于腹部手术的临床价值[J].深圳中西医结合杂志,2015,25(4):136-137.
[4]高金蓉,付武昌.舒芬太尼联合瑞芬太尼全身麻醉对行腹部手术的高龄患者血流动力学、应激反应及镇痛效果的影响[J].中国药房,2016,27(23):3276-3278.
[5]李铁.静脉应用瑞芬太尼在老年腹部手术患者麻醉中的临床效果[J].中国民康医学,2015,27(24):25-26.
[6]何伟.不同剂量右美托咪啶复合异丙酚和瑞芬太尼用于手术中麻醉的效果[J].中国继续医学教育,2018,10(7):58-59.
[7]袁凯东.不同剂量右美托咪啶复合异丙酚和瑞芬太尼用于腹部手术病人麻醉的效果[J].临床医药文献电子杂志,2018,5(5):159-160.
[8]国松,姜万维,郭旭东,等.不同剂量右美托咪定复合丙泊酚-瑞芬太尼对肝功能异常患者腹部手术的麻醉效果与安全性评价[J].中国医药导报,2015,12(34):98-101,121.
[9]蒋亚欧,孙建明,杜海靖.右美托咪啶复合瑞芬太尼在经内镜下逆行胰胆管造影中的应用效果评价[J].实用临床医药杂志,2015,19(19):137-138.
[10]朱鸿昭.右美托咪啶复合异丙酚、瑞芬太尼在腹部手术麻醉中的临床应用效果探讨[J].心理医生,2018,24(11):145.
[11]石进涛,江晨辉,何绮月,等.低浓度地氟烷复合瑞芬太尼对老年患者腹部手术QTc的影响[J].江苏大学学报(医学版),2018,28(3):237-241.
[12]赵莲.瑞芬太尼-异丙酚靶控注射联合右美托咪定在上消化道黏膜切除术、内镜黏膜下剥离术的临床观察[J].吉林医学,2016,37(11):2771-2773.
[13]邱芬.浅谈右美托咪啶联合瑞芬太尼-异丙酚在EMR术中应用效果[J].大家健康(下旬版),2017,11(3):160-161.
[14]李杰雄.右旋美托咪定对行瑞芬太尼复合异丙酚麻醉诱导患儿喉罩(LMA)置入反应的影响[J].中国保健营养,2017,27(7):308.
[15]邵凡,路运本.腹部手术患者应用右美托咪定联合丙泊酚全凭静脉麻醉的意义探究[J].中国卫生标准管理,2018,9(3):132-133.
[16]陈志龙.右美托咪啶复合异丙酚、瑞芬太尼在腹部手术麻醉中的应用[J].深圳中西医结合杂志,2017,27(19):92-93.
[2]田立东,张麟临,刘继强,等.布托啡诺复合右美托咪定对瑞芬太尼诱发术后痛觉过敏的影响[J].中华麻醉学杂志,2015,35(4):401-404.
[3]郑雪琴,车晓琪.右美托咪定复合丙泊酚和瑞芬太尼用于腹部手术的临床价值[J].深圳中西医结合杂志,2015,25(4):136-137.
[4]高金蓉,付武昌.舒芬太尼联合瑞芬太尼全身麻醉对行腹部手术的高龄患者血流动力学、应激反应及镇痛效果的影响[J].中国药房,2016,27(23):3276-3278.
[5]李铁.静脉应用瑞芬太尼在老年腹部手术患者麻醉中的临床效果[J].中国民康医学,2015,27(24):25-26.
[6]何伟.不同剂量右美托咪啶复合异丙酚和瑞芬太尼用于手术中麻醉的效果[J].中国继续医学教育,2018,10(7):58-59.
[7]袁凯东.不同剂量右美托咪啶复合异丙酚和瑞芬太尼用于腹部手术病人麻醉的效果[J].临床医药文献电子杂志,2018,5(5):159-160.
[8]国松,姜万维,郭旭东,等.不同剂量右美托咪定复合丙泊酚-瑞芬太尼对肝功能异常患者腹部手术的麻醉效果与安全性评价[J].中国医药导报,2015,12(34):98-101,121.
[9]蒋亚欧,孙建明,杜海靖.右美托咪啶复合瑞芬太尼在经内镜下逆行胰胆管造影中的应用效果评价[J].实用临床医药杂志,2015,19(19):137-138.
[10]朱鸿昭.右美托咪啶复合异丙酚、瑞芬太尼在腹部手术麻醉中的临床应用效果探讨[J].心理医生,2018,24(11):145.
[11]石进涛,江晨辉,何绮月,等.低浓度地氟烷复合瑞芬太尼对老年患者腹部手术QTc的影响[J].江苏大学学报(医学版),2018,28(3):237-241.
[12]赵莲.瑞芬太尼-异丙酚靶控注射联合右美托咪定在上消化道黏膜切除术、内镜黏膜下剥离术的临床观察[J].吉林医学,2016,37(11):2771-2773.
[13]邱芬.浅谈右美托咪啶联合瑞芬太尼-异丙酚在EMR术中应用效果[J].大家健康(下旬版),2017,11(3):160-161.
[14]李杰雄.右旋美托咪定对行瑞芬太尼复合异丙酚麻醉诱导患儿喉罩(LMA)置入反应的影响[J].中国保健营养,2017,27(7):308.
[15]邵凡,路运本.腹部手术患者应用右美托咪定联合丙泊酚全凭静脉麻醉的意义探究[J].中国卫生标准管理,2018,9(3):132-133.
[16]陈志龙.右美托咪啶复合异丙酚、瑞芬太尼在腹部手术麻醉中的应用[J].深圳中西医结合杂志,2017,27(19):92-93.