中西医改善体外受精-胚胎移植患者子宫内膜容受性研究概况
|
摘要
<正>体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)技术日益成熟,研究显示:目前单次移植的胚胎着床率仍为30%左右~[1]。子宫内膜容受性(Endometrial receptivity,ER)成为胚胎移植成功的关键~[2]。子宫内膜容受性是指子宫内膜对胚
引文
[1]Ferraretti AP,Goossens V,de Mouzon J,et al.Assisted reproductive technology in Europe,2008:results generated from European registers by ESHRE[J].Hum Reprod,2012,27(9):2571-2584.
[2]Murphy CR.Uterine receptivity and the plasma membrane transformation[J].Cell Res,2004,14(4):259-67.
[3]黄向红,谭小军,贺艳坤.生长激素改善冻融胚胎移植周期结局的研究[J].中国实用妇科与产科杂志,2011,27(7):530-533
[4]CHENG F,LI T,WANG QL,et al.Effects of hydrosalpinx on ultrasonographic parameters for endometrial receptivity during the window of implantation measured by power color Doppler ultrasound[J].Int J Clin Exp Med,2015,8(4):6103-6108.
[5]Paule S,Nebl T,Webb AI,et al.Proprotein convertase5/6 cleaves platelet-derived growth factor A in the human endometrium in preparation for embryo implantation[J].Mol Hum Reprod,2015,21(3):262-270.
[6]Cicek MN,Kahyaoglu I,Kahyaoglu S.The comparison of microdose flare-up and multiple dose antagonist protocols based on hCG day estradiol(E2),progesterone(P)and P/E2 ratio among poor responder patients in ICSI-ET cycles[J].Eur Rev Med Pharmacol Sci,2015,19(4):539-544.
[7]Chen S U,Chou C H,Chen M J,et al.Apoptotic effects of high estradiol concentrations on endometrial glandular cells[J].J Clin Endocrinol Metab,2014,99(6):971.
[8]张秦溪,杜伯涛,苗瑞超.经阴道补充雌激素对促排卵期薄型子宫内膜的影响[J].生殖与避孕,2014,34(4):287-291.
[9]游佳英,吴丽钦,何彩平.经阴道补充雌激素对促排卵期薄型子宫内膜的影响[J].北方药学,2016,13(5):25-26
[10]张秋香,陈杨,姚丽.戊酸雌二醇两种给药途径在诱导排卵中对子宫内膜及宫颈黏液的影响[J].中国医学创新,2016,13(3):134-137.
[11]Impicciatore GG,Tiboni GM.Extrapituitary actions of GnRH antagonists:prospects for in vitro fertilization programs[J].Curr Pharm Des,2012,18(3):264-269.
[12]Wu Y,Gao X,Lu X,et al.Endometrial thickness affects the outcome of invitro fertilization and embryo transfer innormal responders after GnRH agonist adiministtration[J].Reprod Biol Endocrinol,2014,12(1):1-5.
[13]Li F,Zhang M,Zhang Y,et al.GnRH analogues mayincrease endometrial Hoxa 10 promoter methylation and affect endometrial receptivity[J].Mol Med Rep,2015,11(1):509-514.
[14]Araujo VR,Gastl MO,Wischral A,et al.In vitro development of bovine secondary follicles in two-and ree-dimensional culture systems using vascular endotheial growth factor,insulinlike growth hormone-1,and growth hormone[J].Theriogenology,2014,82(9):1246-1253.
[15]苏雁,赵纯,凌秀凤,等.重组人生长激素对体外受精-胚胎移植失败患者第二周期妊娠结局的疗效分析[J].中国妇幼保健,2015,30(29):4998-5000.
[16]Bassiouny YA,Dakhly DM,Bassiouny YA,et al.Dose the addition of groth horone to the in vitro fetilization/intracytoplasmi sperm injection antagonist protocol improve outcomes in poor responders?A randomized,controlled trial[J].Obstetrics and Gynecology Depatment,2016,105(3):697-702.
[17]Sher G,Fisch JD.Effect of vaginal sildenafil on the outcome of in vitro fertilization(IVF)after multiple IVF failures attributed to poor endometrial development[J].Fertil Steril,2002,78(5):1073-1076.
[18]孙旸,陈亚琼,兰晓霞,等.枸橼酸西地那非治疗子宫内膜生长不良疗效的系统评价[J].中国药物应用与监测,2016,13(6):333-337;352.
[19]文燕青,池余刚,刘禄斌,等.小剂量阿司匹林对重度宫腔粘连术后子宫内膜容受性及妊娠结局的影响[J].重庆医科大学学报,2017(4):449-452.
[20]杨倩.促排卵过程中应用小剂量阿司匹林对改善子宫内膜发育的研究[J].临床药物治疗杂志,2015,13(3):57-60.
[21]陈丽红,胡继芬,吴建波,等.克罗米芬联合小剂量阿司匹林促排卵的临床疗效及其对子宫内膜的影响[J].中国临床药理学杂志,2015,31(24):2408-2410.
[22]S Acharya,E Yasmin,H Balen.The use of a combination of pentoxifylline and tocopherol in women with a thin endometrium undergoing assisted conception therapies-a report of 20 cases[J].Human Fertility,2009,12(4):198-203.
[23]Kitaya K,Yasuo T,Nakamura Y,et al.Recovery from endometrial thinning and successful pregnancy following vitamin E and C supplementation in infertile woman undergoing myomectomy for diffuse leiomyomatosis of the uterus:a case report[J].Clin Exp Obstet Gynecol,2014,41(3):357-359.
[24]Wilkens J,Male V,Ghazal P,et al.Uterine NK cells regulate endometrial bleeding in women and are suppressed by the progesterone receptor modulator asoprisnil[J].J Immunol,2013,191(5):2226-2235.
[25]Teh WT,Stern C,Chander S,et al.The impact of uterine radiation on subsequent fertility and pregnancy outcomes[J].Biomed Res Int,2014(5):482968.
[26]L Loeb,S Leopold.On the Difference in the Results obtained after Inoculation of tumors into the Individual in which the Tumor had developed spontaneously,and into other Individuals of the same Species[J].J Med Res,1907,17(3):299-319.
[27]刘萍,刘洋,李彩萍.多囊卵巢综合征患者子宫内膜性激素受体表达与早期流产的关系[J]当代医学,2013,19(14):29-30.
[28]Granot I,Gnainsky Y,Dekel N.Endometrial inflammation and effect on implantation improvement and pregnancy outcome[J].Reproduction,2012,144(6):661-668.
[29]Kyurkchiev S,Shterev A,Dimitrov R.Assessment of presence and characteristics of multipotent stromal cells in human endometrium and decidua[J].Reprod Biomed Online,2010,20(3):305-313.
[30]覃桂荣,熊艳敏,李柳铭.宫腔镜子宫内膜微创术对子宫内膜容受性影响的研究[J].实用妇产科杂志,2014,30(2):41-42.
[31]朱一萍,韩凌斐,赵栋,等.宫腔镜检查对反复胚胎种植失败者再次种植妊娠率的影响[J].实用妇产科杂志,2016,32(7):507-510.
[32]Würfel W.Treatment with granulocyte colony-stimulating factor in patients with repetitive implantation failures and/or recurrent spontaneous abortions[J].J ReprodImmunol,2015,108(1):123-135.
[33]Zhao J,Tian T,Zhang Q,et al.Use of granulocyte colony stimulating factor for the treatment of thin endometrium in experimental rats[J].PLoS One,2013,8(12):82375.
[34]Rahmati M,Petitbarat M,Dubanchet S,et al.GranulocyteColony Stimulating Factor related pathways tested on an endometrial exvivo model[J].PLoS One,2014,9(9):102286.
[35]Bertrand-Duchesne MP,Grenier D,Gagnon G.Epidermal growth factor released from platelet-rich plasma promotes endothelial cell proliferation in vitro[J].Periodontal Res,2010,45(1):87-93.
[36]Anitua E,Pelacho B,Prado R,et al.Infiltration of plasma rich in growth factors enhancesin vivo angiogenesis and improves reperfusion and tissue remodeling after severe hind limb ischemia[J].Control Release,2015,28(3):31-39.
[37]Randelli P,Arrigoni P,Ragone V,et al.Platelet rich plasma in arthroscopic rotator cuff repair:a prospective RCT study,2-year follow-up[J].Shoulder Elbow Surg,2011,20(4):518-528.
[38]Reurink G,Goudswaard GJ,Moen MH,et al.Platelet-rich plasma injections in acute muscle injury[J].N Engl J Med,2014,370(26):2546-2547.
[39]Oh DS,Cheon YW,Jeon YR,et al.Activated platelet-rich plasma improves fat graft survival in nude mice:a pilot study[J].Dermatol Surg,2011,37(5):619-625.
[40]常亚杰,张晓莉,杨星,等.富血小板血浆促子宫内膜增殖对妊娠结局的影响[J].实用妇产科杂志,2016,32(6):445-449.
[41]Zhao J,Wang Y,Li Y,et al.Uterine infusion with bone marrow mesenchymal stem cells improves endometrium thickness in a ratmodel of thin endometrium[J].Reprod Sci,2015,22(2):181-188.
[42]Jing Z,Qiong Z,Yong gang W,et al.Rat bone marrow mesenchymalstem cells improve regeneration of thin endometrium in rat[J].FertilSteril,2014,101(2):587-594.
[43]黄羚,刘雁峰,江媚.中西医改善子宫内膜容受性的治疗概况[J].世界中医药,2014(10):31-33.
[44]李海仙,马文敏,高修安,等.中药对PCOS患者行体外受精-胚胎移植助孕的影响[J].中医药学报,2011,39(6):77-79.
[45]王燕婷,陈丽影调经促孕丸配合克罗米芬治疗多囊卵巢综合征性不孕症30例[J]福建中医药,2014,4(3):22-23.
[46]高琦,王松峰,腊晓琳,等.滋肾育胎丸在体外受精-胚胎移植中的效观察[J]甘肃医药,2014,22(12):914-916.
[47]谷向向.补肾法、疏肝法对IVF-ET胚胎着床反复失败患者子宫内膜容受性的影响机制及其比较[J].中医杂志,2015,56(9):782-787.
[48]刘会玲.我国女性不孕症病因的文献回顾性分析[J].河南中医学院,2014,9(8):75.
[49]林树煌,邹小玲,张美玲,等.针灸理疗对PCOS不孕症患者子宫内膜容受性的影响研究[J].湖南中医杂志,2015,31(5):84-86.
[50]严红莲,何淑祯,邢彦君,等.针灸治疗在体外受精—胚胎移植技术中的临床应用研究[J].广州医药,2015,46(1):13-16.
[51]张春晓,连方.论针灸治疗不孕症三级作用靶点[J].辽宁中医药大学学报,2013,15(12):166-168.
[52]李玉,冯晓军,孙伟等.经皮穴位电刺激改善冻融胚胎移植周期患者子宫内膜容受性的临床研究[J].现代中医药,2012,32(3):34-35.
[2]Murphy CR.Uterine receptivity and the plasma membrane transformation[J].Cell Res,2004,14(4):259-67.
[3]黄向红,谭小军,贺艳坤.生长激素改善冻融胚胎移植周期结局的研究[J].中国实用妇科与产科杂志,2011,27(7):530-533
[4]CHENG F,LI T,WANG QL,et al.Effects of hydrosalpinx on ultrasonographic parameters for endometrial receptivity during the window of implantation measured by power color Doppler ultrasound[J].Int J Clin Exp Med,2015,8(4):6103-6108.
[5]Paule S,Nebl T,Webb AI,et al.Proprotein convertase5/6 cleaves platelet-derived growth factor A in the human endometrium in preparation for embryo implantation[J].Mol Hum Reprod,2015,21(3):262-270.
[6]Cicek MN,Kahyaoglu I,Kahyaoglu S.The comparison of microdose flare-up and multiple dose antagonist protocols based on hCG day estradiol(E2),progesterone(P)and P/E2 ratio among poor responder patients in ICSI-ET cycles[J].Eur Rev Med Pharmacol Sci,2015,19(4):539-544.
[7]Chen S U,Chou C H,Chen M J,et al.Apoptotic effects of high estradiol concentrations on endometrial glandular cells[J].J Clin Endocrinol Metab,2014,99(6):971.
[8]张秦溪,杜伯涛,苗瑞超.经阴道补充雌激素对促排卵期薄型子宫内膜的影响[J].生殖与避孕,2014,34(4):287-291.
[9]游佳英,吴丽钦,何彩平.经阴道补充雌激素对促排卵期薄型子宫内膜的影响[J].北方药学,2016,13(5):25-26
[10]张秋香,陈杨,姚丽.戊酸雌二醇两种给药途径在诱导排卵中对子宫内膜及宫颈黏液的影响[J].中国医学创新,2016,13(3):134-137.
[11]Impicciatore GG,Tiboni GM.Extrapituitary actions of GnRH antagonists:prospects for in vitro fertilization programs[J].Curr Pharm Des,2012,18(3):264-269.
[12]Wu Y,Gao X,Lu X,et al.Endometrial thickness affects the outcome of invitro fertilization and embryo transfer innormal responders after GnRH agonist adiministtration[J].Reprod Biol Endocrinol,2014,12(1):1-5.
[13]Li F,Zhang M,Zhang Y,et al.GnRH analogues mayincrease endometrial Hoxa 10 promoter methylation and affect endometrial receptivity[J].Mol Med Rep,2015,11(1):509-514.
[14]Araujo VR,Gastl MO,Wischral A,et al.In vitro development of bovine secondary follicles in two-and ree-dimensional culture systems using vascular endotheial growth factor,insulinlike growth hormone-1,and growth hormone[J].Theriogenology,2014,82(9):1246-1253.
[15]苏雁,赵纯,凌秀凤,等.重组人生长激素对体外受精-胚胎移植失败患者第二周期妊娠结局的疗效分析[J].中国妇幼保健,2015,30(29):4998-5000.
[16]Bassiouny YA,Dakhly DM,Bassiouny YA,et al.Dose the addition of groth horone to the in vitro fetilization/intracytoplasmi sperm injection antagonist protocol improve outcomes in poor responders?A randomized,controlled trial[J].Obstetrics and Gynecology Depatment,2016,105(3):697-702.
[17]Sher G,Fisch JD.Effect of vaginal sildenafil on the outcome of in vitro fertilization(IVF)after multiple IVF failures attributed to poor endometrial development[J].Fertil Steril,2002,78(5):1073-1076.
[18]孙旸,陈亚琼,兰晓霞,等.枸橼酸西地那非治疗子宫内膜生长不良疗效的系统评价[J].中国药物应用与监测,2016,13(6):333-337;352.
[19]文燕青,池余刚,刘禄斌,等.小剂量阿司匹林对重度宫腔粘连术后子宫内膜容受性及妊娠结局的影响[J].重庆医科大学学报,2017(4):449-452.
[20]杨倩.促排卵过程中应用小剂量阿司匹林对改善子宫内膜发育的研究[J].临床药物治疗杂志,2015,13(3):57-60.
[21]陈丽红,胡继芬,吴建波,等.克罗米芬联合小剂量阿司匹林促排卵的临床疗效及其对子宫内膜的影响[J].中国临床药理学杂志,2015,31(24):2408-2410.
[22]S Acharya,E Yasmin,H Balen.The use of a combination of pentoxifylline and tocopherol in women with a thin endometrium undergoing assisted conception therapies-a report of 20 cases[J].Human Fertility,2009,12(4):198-203.
[23]Kitaya K,Yasuo T,Nakamura Y,et al.Recovery from endometrial thinning and successful pregnancy following vitamin E and C supplementation in infertile woman undergoing myomectomy for diffuse leiomyomatosis of the uterus:a case report[J].Clin Exp Obstet Gynecol,2014,41(3):357-359.
[24]Wilkens J,Male V,Ghazal P,et al.Uterine NK cells regulate endometrial bleeding in women and are suppressed by the progesterone receptor modulator asoprisnil[J].J Immunol,2013,191(5):2226-2235.
[25]Teh WT,Stern C,Chander S,et al.The impact of uterine radiation on subsequent fertility and pregnancy outcomes[J].Biomed Res Int,2014(5):482968.
[26]L Loeb,S Leopold.On the Difference in the Results obtained after Inoculation of tumors into the Individual in which the Tumor had developed spontaneously,and into other Individuals of the same Species[J].J Med Res,1907,17(3):299-319.
[27]刘萍,刘洋,李彩萍.多囊卵巢综合征患者子宫内膜性激素受体表达与早期流产的关系[J]当代医学,2013,19(14):29-30.
[28]Granot I,Gnainsky Y,Dekel N.Endometrial inflammation and effect on implantation improvement and pregnancy outcome[J].Reproduction,2012,144(6):661-668.
[29]Kyurkchiev S,Shterev A,Dimitrov R.Assessment of presence and characteristics of multipotent stromal cells in human endometrium and decidua[J].Reprod Biomed Online,2010,20(3):305-313.
[30]覃桂荣,熊艳敏,李柳铭.宫腔镜子宫内膜微创术对子宫内膜容受性影响的研究[J].实用妇产科杂志,2014,30(2):41-42.
[31]朱一萍,韩凌斐,赵栋,等.宫腔镜检查对反复胚胎种植失败者再次种植妊娠率的影响[J].实用妇产科杂志,2016,32(7):507-510.
[32]Würfel W.Treatment with granulocyte colony-stimulating factor in patients with repetitive implantation failures and/or recurrent spontaneous abortions[J].J ReprodImmunol,2015,108(1):123-135.
[33]Zhao J,Tian T,Zhang Q,et al.Use of granulocyte colony stimulating factor for the treatment of thin endometrium in experimental rats[J].PLoS One,2013,8(12):82375.
[34]Rahmati M,Petitbarat M,Dubanchet S,et al.GranulocyteColony Stimulating Factor related pathways tested on an endometrial exvivo model[J].PLoS One,2014,9(9):102286.
[35]Bertrand-Duchesne MP,Grenier D,Gagnon G.Epidermal growth factor released from platelet-rich plasma promotes endothelial cell proliferation in vitro[J].Periodontal Res,2010,45(1):87-93.
[36]Anitua E,Pelacho B,Prado R,et al.Infiltration of plasma rich in growth factors enhancesin vivo angiogenesis and improves reperfusion and tissue remodeling after severe hind limb ischemia[J].Control Release,2015,28(3):31-39.
[37]Randelli P,Arrigoni P,Ragone V,et al.Platelet rich plasma in arthroscopic rotator cuff repair:a prospective RCT study,2-year follow-up[J].Shoulder Elbow Surg,2011,20(4):518-528.
[38]Reurink G,Goudswaard GJ,Moen MH,et al.Platelet-rich plasma injections in acute muscle injury[J].N Engl J Med,2014,370(26):2546-2547.
[39]Oh DS,Cheon YW,Jeon YR,et al.Activated platelet-rich plasma improves fat graft survival in nude mice:a pilot study[J].Dermatol Surg,2011,37(5):619-625.
[40]常亚杰,张晓莉,杨星,等.富血小板血浆促子宫内膜增殖对妊娠结局的影响[J].实用妇产科杂志,2016,32(6):445-449.
[41]Zhao J,Wang Y,Li Y,et al.Uterine infusion with bone marrow mesenchymal stem cells improves endometrium thickness in a ratmodel of thin endometrium[J].Reprod Sci,2015,22(2):181-188.
[42]Jing Z,Qiong Z,Yong gang W,et al.Rat bone marrow mesenchymalstem cells improve regeneration of thin endometrium in rat[J].FertilSteril,2014,101(2):587-594.
[43]黄羚,刘雁峰,江媚.中西医改善子宫内膜容受性的治疗概况[J].世界中医药,2014(10):31-33.
[44]李海仙,马文敏,高修安,等.中药对PCOS患者行体外受精-胚胎移植助孕的影响[J].中医药学报,2011,39(6):77-79.
[45]王燕婷,陈丽影调经促孕丸配合克罗米芬治疗多囊卵巢综合征性不孕症30例[J]福建中医药,2014,4(3):22-23.
[46]高琦,王松峰,腊晓琳,等.滋肾育胎丸在体外受精-胚胎移植中的效观察[J]甘肃医药,2014,22(12):914-916.
[47]谷向向.补肾法、疏肝法对IVF-ET胚胎着床反复失败患者子宫内膜容受性的影响机制及其比较[J].中医杂志,2015,56(9):782-787.
[48]刘会玲.我国女性不孕症病因的文献回顾性分析[J].河南中医学院,2014,9(8):75.
[49]林树煌,邹小玲,张美玲,等.针灸理疗对PCOS不孕症患者子宫内膜容受性的影响研究[J].湖南中医杂志,2015,31(5):84-86.
[50]严红莲,何淑祯,邢彦君,等.针灸治疗在体外受精—胚胎移植技术中的临床应用研究[J].广州医药,2015,46(1):13-16.
[51]张春晓,连方.论针灸治疗不孕症三级作用靶点[J].辽宁中医药大学学报,2013,15(12):166-168.
[52]李玉,冯晓军,孙伟等.经皮穴位电刺激改善冻融胚胎移植周期患者子宫内膜容受性的临床研究[J].现代中医药,2012,32(3):34-35.