摘要
目的探究硝苯地平缓释片联合厄贝沙坦片治疗原发性高血压的临床效果。方法 128例原发性高血压患者,根据治疗药物不同分为对照组和观察组,每组64例。对照组患者采用硝苯地平缓释片联合卡托普利片进行治疗,观察组患者采用硝苯地平缓释片联合厄贝沙坦片进行治疗。观察比较两组患者的治疗效果及不良反应发生情况。结果观察组患者的治疗总有效率为96.88%(62/64),显著高于对照组的87.50%(56/64),差异具有统计学意义(P<0.05)。观察组患者的不良发应发生率为3.13%(2/64),显著低于对照组的12.50%(8/64),差异具有统计学意义(P<0.05)。结论硝苯地平缓释片联合厄贝沙坦片治疗原发性高血压临床治疗效果更加显著,具有一定的临床推广应用价值。
Objective To investigate the clinical effect of Extended Release Nifedipine Tablets combined with Irbesartan Tablets in the treatment of essential hypertension. Methods A total of 128 patients with essential hypertension were divided into control group and observation group according to the different therapeutic drugs, 64 cases in each group. The control group was treated with Extended Release Nifedipine Tablets and Captopril Tablets, and the observation group was treated with Extended Release Nifedipine Tablets combined with Irbesartan Tablets. The therapeutic effect and adverse reactions between the two groups were observed and compared. Results The total effective rate of treatment in the observation group was 96.88%(62/64), which was significantly higher than 87.50%(56/64), the difference was statistically significant(P<0.05). The incidence of adverse reactions in the observation group was 3.13%(2/64), which was significantly lower than 12.50%(8/64), the difference was statistically significant(P<0.05). Conclusion The clinical treatment effect of Extended Release Nifedipine Tablets combined with Irbesartan Tablets in the treatment of essential hypertension is more significant, so it has a certain clinical application value.
引文
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