硝苯地平缓释片联合厄贝沙坦片治疗原发性高血压临床疗效观察
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摘要
目的探究硝苯地平缓释片联合厄贝沙坦片治疗原发性高血压的临床效果。方法 128例原发性高血压患者,根据治疗药物不同分为对照组和观察组,每组64例。对照组患者采用硝苯地平缓释片联合卡托普利片进行治疗,观察组患者采用硝苯地平缓释片联合厄贝沙坦片进行治疗。观察比较两组患者的治疗效果及不良反应发生情况。结果观察组患者的治疗总有效率为96.88%(62/64),显著高于对照组的87.50%(56/64),差异具有统计学意义(P<0.05)。观察组患者的不良发应发生率为3.13%(2/64),显著低于对照组的12.50%(8/64),差异具有统计学意义(P<0.05)。结论硝苯地平缓释片联合厄贝沙坦片治疗原发性高血压临床治疗效果更加显著,具有一定的临床推广应用价值。
Objective To investigate the clinical effect of Extended Release Nifedipine Tablets combined with Irbesartan Tablets in the treatment of essential hypertension. Methods A total of 128 patients with essential hypertension were divided into control group and observation group according to the different therapeutic drugs, 64 cases in each group. The control group was treated with Extended Release Nifedipine Tablets and Captopril Tablets, and the observation group was treated with Extended Release Nifedipine Tablets combined with Irbesartan Tablets. The therapeutic effect and adverse reactions between the two groups were observed and compared. Results The total effective rate of treatment in the observation group was 96.88%(62/64), which was significantly higher than 87.50%(56/64), the difference was statistically significant(P<0.05). The incidence of adverse reactions in the observation group was 3.13%(2/64), which was significantly lower than 12.50%(8/64), the difference was statistically significant(P<0.05). Conclusion The clinical treatment effect of Extended Release Nifedipine Tablets combined with Irbesartan Tablets in the treatment of essential hypertension is more significant, so it has a certain clinical application value.
Objective To investigate the clinical effect of Extended Release Nifedipine Tablets combined with Irbesartan Tablets in the treatment of essential hypertension. Methods A total of 128 patients with essential hypertension were divided into control group and observation group according to the different therapeutic drugs, 64 cases in each group. The control group was treated with Extended Release Nifedipine Tablets and Captopril Tablets, and the observation group was treated with Extended Release Nifedipine Tablets combined with Irbesartan Tablets. The therapeutic effect and adverse reactions between the two groups were observed and compared. Results The total effective rate of treatment in the observation group was 96.88%(62/64), which was significantly higher than 87.50%(56/64), the difference was statistically significant(P<0.05). The incidence of adverse reactions in the observation group was 3.13%(2/64), which was significantly lower than 12.50%(8/64), the difference was statistically significant(P<0.05). Conclusion The clinical treatment effect of Extended Release Nifedipine Tablets combined with Irbesartan Tablets in the treatment of essential hypertension is more significant, so it has a certain clinical application value.
引文
[1]朱沪沛,孙燕.原发性高血压的治疗管理与效果研究.中医药管理杂志,2018,26(1):188-190.
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[5]吴萍.苯磺酸氨氯地平与硝苯地平缓释片治疗原发性高血压临床疗效对比.慢性病学杂志,2017,18(10):1137-1138.
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[8]李培友.缬沙坦联合硝苯地平缓释片治疗原发性高血压临床疗效分析.中外女性健康研究,2017(13):109,117.
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[10]孙师云.厄贝沙坦片联合硝苯地平缓释片治疗原发性高血压临床疗效分析.深圳中西医结合杂志,2015,25(18):143-144.
[11]丁秀娟.硝苯地平联合厄贝沙坦片治疗原发性高血压临床疗效观察.心血管病防治知识(学术版),2015(5):24-25.
[12]艾国锋.硝苯地平合并厄贝沙坦片治疗原发性高血压临床疗效观察.中国卫生标准管理,2015,6(4):112-113.
[13]杨寿山.硝苯地平联合厄贝沙坦片治疗原发性高血压临床疗效观察.中国社区医师(医学专业),2013,15(9):56-57.
[14]李涵,郝东宁,马肃.神经导航辅助微创手术治疗老年高血压性基底节出血的临床疗效.卒中与神经疾病,2018(1):64-67.
[15]刘长明,刘荣.瑞舒伐他汀钙片治疗高血压脑出血的临床研究.中国临床药理学杂志,2018,34(3):209-211.
[2]高颖.缬沙坦联合硝苯地平控释片治疗原发性高血压的临床疗效观察.中西医结合心血管病电子杂志,2018(1):39.
[3]范振兴.硝苯地平缓释片Ⅱ治疗原发性高血压的疗效及评价.药学研究,2017,36(12):739-741.
[4]国仕刚.缬沙坦联合硝苯地平控释片治疗原发性高血压的临床疗效观察.中国现代药物应用,2017,11(21):105-106.
[5]吴萍.苯磺酸氨氯地平与硝苯地平缓释片治疗原发性高血压临床疗效对比.慢性病学杂志,2017,18(10):1137-1138.
[6]郑富文,徐国旺.硝苯地平控释片治疗原发性高血压伴稳定型心绞痛的临床疗效观察.中国实用医药,2017,12(22):115-117.
[7]陈秋波.硝苯地平联合厄贝沙坦片治疗原发性高血压临床疗效观察.中国社区医师,2017,33(20):28,30.
[8]李培友.缬沙坦联合硝苯地平缓释片治疗原发性高血压临床疗效分析.中外女性健康研究,2017(13):109,117.
[9]徐俊凤.硝苯地平联合厄贝沙坦片治疗原发性高血压的临床观察.中西医结合心血管病电子杂志,2016,4(20):9-10.
[10]孙师云.厄贝沙坦片联合硝苯地平缓释片治疗原发性高血压临床疗效分析.深圳中西医结合杂志,2015,25(18):143-144.
[11]丁秀娟.硝苯地平联合厄贝沙坦片治疗原发性高血压临床疗效观察.心血管病防治知识(学术版),2015(5):24-25.
[12]艾国锋.硝苯地平合并厄贝沙坦片治疗原发性高血压临床疗效观察.中国卫生标准管理,2015,6(4):112-113.
[13]杨寿山.硝苯地平联合厄贝沙坦片治疗原发性高血压临床疗效观察.中国社区医师(医学专业),2013,15(9):56-57.
[14]李涵,郝东宁,马肃.神经导航辅助微创手术治疗老年高血压性基底节出血的临床疗效.卒中与神经疾病,2018(1):64-67.
[15]刘长明,刘荣.瑞舒伐他汀钙片治疗高血压脑出血的临床研究.中国临床药理学杂志,2018,34(3):209-211.