郑州市二七区2016年医院就诊人群HCV感染状况调查
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摘要
目的了解郑州市二七区综合医院和传染病医院就诊人群HCV感染状况,为其他地区开展HCV感染状况调查提供参考。方法采用随机抽样,抽取辖区2级及以上综合医院和传染病医院各一家,比较2016年全年就诊者丙肝阳性率。2016年1月在综合医院按照年龄和性别分层抽样收集1 000例就诊者(肝病科、消化科、感染科等与肝炎有密切关系的科室就诊者除外)进行丙型肝炎抗体和核酸的检测,传染病医院2016年全年就诊者丙型肝炎抗体和核酸的检测。结果 2016年二七区综合医院和传染病医院就诊人群的丙肝检测阳性率分别是0.71%(304/42970)和11.25%(1 932/17 166),差异具有统计学意义(χ~2=3811.572,P=0.000)。1 000例综合医院普通就诊人群的抗-HCV阳性率0.80%(8/1000),HCV RNA阳性率0.70%(7/1000),与2012年河南省开展丙肝人群调查数据相比,差异无统计学意义。结论郑州市二七区综合医院普通就诊人群丙型肝炎呈低流行状态,综合医院普通就诊人群HCV阳性率可以在一定程度上反映普通人群阳性率。
Objective To understand the epidemiological characteristics of hepatitis C among the crowd seeking medical in general hospital and the infectious disease hospital in Erqi District of Zhengzhou and provide the reference of investigating hepatitis C for the other areas. Methods Random sampling was used to select one general hospital and one infectious disease hospital in Erqi District of Zhengzhou. The positive rates of HCV in 2016 were compared in two hospitals. Investagation was done in the crowd seeking medical in the general hospital by age and sex stratified sampling which sample size was 1 000 cases. Blood samples were collected and detected for anti-HCV and hepatitis C virus. All patients in infectious disease hospital were detected all the year. Results The positive rates of HCV in the crowd seeking medical were respectively0. 71%( 304/42 970) and 11. 25%( 1 932/17 166) in 2016 in general hospital and the infectious disease hospital,which was significant difference in statistics( χ~2= 3811. 572,P = 0. 000). In 1 000 cases from general crowd seeking medical,the positive rates of anti-HCV and HCV RNA were 0. 80%( 8/1 000) and0. 70%( 7/1 000),respectively. Compared with the data of HCV in Hennan province in 2012,there were no significant difference in statistics. Conclusion It was low prevalent for HCV infection among the general crowd seeking medical in Erqi District of Zhengzhou. The HCV positive rate among general populationcould be reflected in some extent by that among the general crowd seeking medical of general hospital.
Objective To understand the epidemiological characteristics of hepatitis C among the crowd seeking medical in general hospital and the infectious disease hospital in Erqi District of Zhengzhou and provide the reference of investigating hepatitis C for the other areas. Methods Random sampling was used to select one general hospital and one infectious disease hospital in Erqi District of Zhengzhou. The positive rates of HCV in 2016 were compared in two hospitals. Investagation was done in the crowd seeking medical in the general hospital by age and sex stratified sampling which sample size was 1 000 cases. Blood samples were collected and detected for anti-HCV and hepatitis C virus. All patients in infectious disease hospital were detected all the year. Results The positive rates of HCV in the crowd seeking medical were respectively0. 71%( 304/42 970) and 11. 25%( 1 932/17 166) in 2016 in general hospital and the infectious disease hospital,which was significant difference in statistics( χ~2= 3811. 572,P = 0. 000). In 1 000 cases from general crowd seeking medical,the positive rates of anti-HCV and HCV RNA were 0. 80%( 8/1 000) and0. 70%( 7/1 000),respectively. Compared with the data of HCV in Hennan province in 2012,there were no significant difference in statistics. Conclusion It was low prevalent for HCV infection among the general crowd seeking medical in Erqi District of Zhengzhou. The HCV positive rate among general populationcould be reflected in some extent by that among the general crowd seeking medical of general hospital.
引文
[1]河南统计局,国家统计局河南调查总队.河南省统计年鉴2011[M].北京:中国统计出版社,2011:105.
[2]樊盼英,孙定勇,马彦民,等.河南省丙型肝炎流行特征研究[J].中华流行病学杂志,2013,34(6):557-559.
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[5]陈园生,李黎,崔富强,等.中国丙型肝炎血清流行病学研究[J].中华流行病学杂志,201l,32(9):888-891.
[6]崔为国,薛秀娟,刘春华,等.2012年河南省丙型肝炎病毒感染状况及基因型分布调查[J].中华预防医学杂志,2013,47(6):518-522.
[7]项丽芬,唐仁海,杨跃诚,等.云南省德宏州社区居民丙型肝炎病毒感染率及影响因素研究[J].中国初级卫生保健,2013,27(5):80-82.
[8]陈佳.3762例住院患者丙型肝炎病毒抗体阳性率统计分析[J].检验医学与临床,2012,9(6):736.
[9]关幼华,肖志超,粱玉.佛山地区人群血清丙型肝炎病毒抗体的阳性率及检测意义[J].检验医学与临床,2009,6(8):561-562.
[10]王冬艳,王绚.北京市某区血清丙型肝炎抗体阳性率并探讨检测方法问题[J].中国卫生检验杂志,2008,18(8):562-563.
[11]刘凤娟,黄舒燕,高艳青,等.北京市328例在押人员艾滋病、梅毒、乙丙型肝炎感染率检测[J].临床荟萃,2010,25(9):793-794.
[12]岳秋梅.承德市市区2005-2009年食品与公共场所从业人员丙型肝炎病毒感染情况[J].职业与健康,2010:1134-1135.
[13]刘威.2008-2011年辽源市无偿献血者丙肝抗体阳性率状况调查[J].中外医疗,2012,30:117-119.
[2]樊盼英,孙定勇,马彦民,等.河南省丙型肝炎流行特征研究[J].中华流行病学杂志,2013,34(6):557-559.
[3]河南统计局,国家统计局河南调查总队.河南省统计年鉴2012[M].北京:中国统计出版社,2012.
[4]WHO第63届世界卫生大会.病毒性肝炎:秘书处的报告[EB/OL].[2013-01-22].http://www.docin.com/p-289449237.html.
[5]陈园生,李黎,崔富强,等.中国丙型肝炎血清流行病学研究[J].中华流行病学杂志,201l,32(9):888-891.
[6]崔为国,薛秀娟,刘春华,等.2012年河南省丙型肝炎病毒感染状况及基因型分布调查[J].中华预防医学杂志,2013,47(6):518-522.
[7]项丽芬,唐仁海,杨跃诚,等.云南省德宏州社区居民丙型肝炎病毒感染率及影响因素研究[J].中国初级卫生保健,2013,27(5):80-82.
[8]陈佳.3762例住院患者丙型肝炎病毒抗体阳性率统计分析[J].检验医学与临床,2012,9(6):736.
[9]关幼华,肖志超,粱玉.佛山地区人群血清丙型肝炎病毒抗体的阳性率及检测意义[J].检验医学与临床,2009,6(8):561-562.
[10]王冬艳,王绚.北京市某区血清丙型肝炎抗体阳性率并探讨检测方法问题[J].中国卫生检验杂志,2008,18(8):562-563.
[11]刘凤娟,黄舒燕,高艳青,等.北京市328例在押人员艾滋病、梅毒、乙丙型肝炎感染率检测[J].临床荟萃,2010,25(9):793-794.
[12]岳秋梅.承德市市区2005-2009年食品与公共场所从业人员丙型肝炎病毒感染情况[J].职业与健康,2010:1134-1135.
[13]刘威.2008-2011年辽源市无偿献血者丙肝抗体阳性率状况调查[J].中外医疗,2012,30:117-119.