养心汤加减治疗心脾两虚型不寐病的临床疗效观察
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摘要
目的:观察养心汤加减治疗心脾两虚型不寐病的临床疗效。方法:选取2016年9月-2018年4月武汉市中医医院脑病科门诊就诊的96例心脾两虚型不寐病患者作为本次的研究对象,按随机数字表法将所选的患者分为治疗组和对照组,治疗组54例,予养心汤加减治疗。对照组42例,予右佐匹克隆片治疗,疗程均为3个月。结果:进行治疗前后匹兹堡睡眠质量指数(PSQI)评分,结果治疗组总有效率为87.5%,对照组为64.3%,两组比较差异有统计学意义(P <0. 05)。两组睡眠质量比较,治疗组PSQI各因子及总分低于对照组(P <0. 05)。治疗前两组中医症状积分比较差异无统计学意义(P> 0.05);治疗后,治疗组各中医症状积分均低于治疗前(P <0.05),对照组仅入睡困难一项积分低于治疗前(P <0.05),治疗组各中医症状积分均低于对照组(P <0.05)。结论:养心汤加减治疗心脾两虚型不寐病能有效改善睡眠质量,临床疗效确切。
Objective: To observe clinical efficacy of the Yangxin decoction( 养心汤) on insomnia of the Xinpi Liangxu type( 心脾两虚型). Methods: From September 2016 to April 2018, 96 cases were divided into two groups. 54 cases in the treatment group were given the Yangxin decoction. 42 cases in the control group was given dexzopiclone tablets, for 3 months. Results: The Pittsburgh Sleep Quality Index(PSQI) scores before and after treatment showed a efficiency of 87.5% in the treatment group and 64.3% in the control group(P < 0.05).There was no significant difference in the scores of TCM symptoms between two groups before treatment(P>0.05). After treatment, the scores of TCM symptoms in the treatment group were lower than before treatment(P<0.05). The scores of difficulty in falling asleep in the control group were lower than before treatment(P<0.05). The scores of TCM symptoms in the treatment group were lower than those in the control group(P<0.05). Conclusion: The Yangxin decoction on insomnia of the Xinpi Liangxu type can effectively improve sleep quality.
Objective: To observe clinical efficacy of the Yangxin decoction( 养心汤) on insomnia of the Xinpi Liangxu type( 心脾两虚型). Methods: From September 2016 to April 2018, 96 cases were divided into two groups. 54 cases in the treatment group were given the Yangxin decoction. 42 cases in the control group was given dexzopiclone tablets, for 3 months. Results: The Pittsburgh Sleep Quality Index(PSQI) scores before and after treatment showed a efficiency of 87.5% in the treatment group and 64.3% in the control group(P < 0.05).There was no significant difference in the scores of TCM symptoms between two groups before treatment(P>0.05). After treatment, the scores of TCM symptoms in the treatment group were lower than before treatment(P<0.05). The scores of difficulty in falling asleep in the control group were lower than before treatment(P<0.05). The scores of TCM symptoms in the treatment group were lower than those in the control group(P<0.05). Conclusion: The Yangxin decoction on insomnia of the Xinpi Liangxu type can effectively improve sleep quality.
引文
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[2]李艳,刘敏琦.养肝益肾安神颗粒配合耳穴贴压治疗中风后失眠的临床研究[J].中医临床研究,2017,9(33):46-48.
[3]应卫真,刘灵波,王功磊.归脾汤联合柏子养心丸治疗心脾两虚型失眠疗效观察[J].实用中医药杂志,2018,34(1):34-35.
[4]顾兆一.丹栀逍遥散合黄连温胆汤加减治疗失眠临床观察[J].中医临床研究,2015,7(7):87-88.
[5]中华医学会精神病学分会.中国精神障碍分类与诊断标准第三版(精神障碍分类)[J].中华精神科杂志,2001,34(3):184-188.
[6]中华人民共和国卫生部.中药新药临床研究指导原则[M].北京:中国医药科技出版社,1993:186.
[7]陈传铭.定魂汤治疗心肝血虚失眠的临床观察[J].中国实用医药,2017,12(34):8-10.
[8]王肯堂.证治准绳[M].上海:上海科技出版社,1959:408.
[9]李巍,马西虎,黄志惠.养心汤治疗顽固性失眠60例[J].甘肃中医,2009,22(4):22-23.
[10]范增光,杨建飞.中药养心汤的应用研究进展[J].中国中医急症,2016,25(12):2301-2303.