癫痫发作后J波综合征的分布特征及其相关因素
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摘要
目的观察癫痫发作后J波综合征的分布特征及其相关因素。方法搜集2015年6月~2016年6月在陕西省人民医院住院的癫痫发作出现J波综合征患者35例,与同期入院癫痫发作心电图无变化的患者35例为对照组,做对比分析。结果 35例癫痫患者出现J波综合征,J波明显7例(占20%),JT部分融合J波尚可辨认12例(占34%),JT完全融合,J波不可分辨16例(占46%)。其中下壁导联出现J波者17例(占49%),前壁导联出现J波18例(占51%)。J波综合征组与对照组对比,超敏C反应蛋白(hs-CRP)具有统计学差异[(5.4±0.9)mmol/L vs.(3.3±0.7)mmol/L,P<0.05],余无统计学差异。Pearson相关性分析示癫痫患者出现J波综合征与hs-CRP具有相关性(r=0.28,P=0.036)。结论癫痫发作2~3 min后部分患者出现J波综合征,J波形态多样,出现在下壁和前壁导联,J波综合征的相关因素是hs-CRP。
AIM To analyze the distribution characteristics and related factors of epilepsy with J wave syndrome. METHODS Thirty-five epilepsy patients with J wave syndrome from June 2015 to June 2016 were compared with 35 epilepsy patients without J wave syndrome. RESULTS Among the 35 epilepsy patients with J wave syndrome,the J wave was obvious in 7 patients( 20%),the J wave could still be identified in 12 patients( 34%) with partial fusion of J wave and T wave. The J wave could not be identified in 16 patients( 46%) with total fusion of J wave and T wave. The inferior leads showed J wave in 17 patients( 49%) and anterior leads showed J wave in 18 patients( 51%). Significant differences were found in hs CRP between the group of J wave and group of no J wave [( 5. 4 ± 0. 9) mmol/L vs.( 3. 3 ± 0. 7) mmol/L,P < 0. 05]. Pearson correlation analysis showed hs-CRP was associated with J wave syndrome in patients with epilepsy( r = 0. 28,P = 0. 036). CONCLUSION J wave syndrome occurs in some patients 2-3 minutes after epilepsy. J wave occurs in the inferior wall and the anterior wall. hs-CRP was associated with J wave syndrom in patients with epilepsy.
AIM To analyze the distribution characteristics and related factors of epilepsy with J wave syndrome. METHODS Thirty-five epilepsy patients with J wave syndrome from June 2015 to June 2016 were compared with 35 epilepsy patients without J wave syndrome. RESULTS Among the 35 epilepsy patients with J wave syndrome,the J wave was obvious in 7 patients( 20%),the J wave could still be identified in 12 patients( 34%) with partial fusion of J wave and T wave. The J wave could not be identified in 16 patients( 46%) with total fusion of J wave and T wave. The inferior leads showed J wave in 17 patients( 49%) and anterior leads showed J wave in 18 patients( 51%). Significant differences were found in hs CRP between the group of J wave and group of no J wave [( 5. 4 ± 0. 9) mmol/L vs.( 3. 3 ± 0. 7) mmol/L,P < 0. 05]. Pearson correlation analysis showed hs-CRP was associated with J wave syndrome in patients with epilepsy( r = 0. 28,P = 0. 036). CONCLUSION J wave syndrome occurs in some patients 2-3 minutes after epilepsy. J wave occurs in the inferior wall and the anterior wall. hs-CRP was associated with J wave syndrom in patients with epilepsy.
引文
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[2]王东琦.心电图心室复极波的细胞离子流机制与临床[J].中华心律失常学杂志,2005,9(6):478-482.
[3]严干新,姚东海,王东琦.J波与J波综合征[J].中华心律失常学杂志,2004,8(6):360-365.
[4]胡喜田.早期复极综合征的研究进展[J].实用心电学杂志,2015,24(1):1-8.
[5]Lin X,O’Malley HA,Chen C,et al.Scn1b deletion leads to increased tetrodotoxin-sensitive sodium current,altered intracellular calcium homeostasis and arrhythmias in murine hearts[J].J Physiol,2015,593(6):1369-1407.
[6]O’Malley HA,Lsom LL.Isom Sodium channelβsubunits:emerging targets in channelopayhies[J].Annu Rev Physiol,2015,77(4):481-504.
[7]冯天捷,陈柯萍,任晓庆.高敏C反应蛋白对室性心律失常发作的预测作用[J].中国循环杂志,2014,29(2):124-128.