小儿脊髓拴系综合征术后疼痛干预模式的研究
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摘要
对于脊髓拴系综合征的患儿来说,手术是目前治疗此病的唯一途径,但手术较复杂、切口长,术后疼痛明显。疼痛会对小儿产生负面影响,因此探寻术后有效的疼痛干预模式对于患儿是十分重要的。
     目的
     对接受脊髓拴系手术的患儿实施以家庭为中心护理和多种非药物干预相结合的疼痛干预模式,探索这种干预模式对患儿术后疼痛、焦虑、及患儿家长术后焦虑、护理服务满意度的干预效果。并通过质性研究了解护理人员在小儿疼痛管理中的真实感受,为以后疼痛管理服务提供依据。
     方法
     1研究对象
     采用非同期对照和方便抽样的方法,抽取郑州大学第三附属医院3岁到12岁接受脊髓拴系手术患儿及家长各40例,以2011年10月至2012年3月期间接受脊髓拴系手术患儿及家长各20例为对照组;2012年3月至2012年11月的接受脊髓拴系手术患儿及家长各20例为干预组,质性研究采用立意采样法,有目的地选取儿科护士,共8名护士参与访谈。
     2方法
     对照组采用目前小儿外科病房的普通护理模式,家长接受常规健康教育及术后护理。干预组采用以家庭为中心护理和多种非药物干预相结合的疼痛干预模式。分别用Wong—Banker面部表情量表(Faces Pain Scale, FPS)、改良耶鲁围手术期焦虑量表(The modified Yale Preoperative Anxiety Scale,YPAS)、状态焦虑问卷(State Anxiety Inventory, SAI)、纽卡斯尔护理服务满意度量表(Newcastle satisfaction with nursing scales, NSNS)来评价干预后两组患儿术后疼痛、术后焦虑、患儿家长术后焦虑、护理服务满意度。采用质性研究对8名儿科护士进行深度访谈。
     3统计方法
     使用SPSS17.0统计软件包处理所有数据,计量资料如年龄等采用均数、标准差描述,计数资料如性别等采用频数描述;采用两独立样本Mann-Whitney U检验、两独立样本t检验比较两组患儿一般资料中计量资料之间的差异有无统计学意义,采用Fisher确切概率法比较两组患儿一般资料中计数资料之间的差异有无统计学意义。干预前采用两独立样本t检验比较两组患儿家长焦虑状况有无差异,干预后采用Mann-WhitneyU非参数秩和检验、两独立样本t检验分析对照组和干预组患儿疼痛评分、患儿术后焦虑、患儿家长术后焦虑状况、护理满意度有无差异。检验水准α=0.05。
     结果
     1两组患儿一般资料比较
     本研究中对对照组和干预组的年龄、年龄构成、性别、居住地、兄弟姐妹等一般资料进行比较,差异均无统计学意义(P>0.05)。
     2两组患儿术后疼痛和术后焦虑得分比较
     干预后术后1小时、术后24小时两组患儿疼痛评分差异无统计学意义(P>0.05);术后8小时、术后16小时干预组疼痛评分低于对照组且疼痛评分差异有统计学意义(P<0.05)。干预后两组患儿术后焦虑进行比较,干预组比对照组患儿术后焦虑得分低,差异有统计学意义(P<0.05)。
     3两组家长干预前焦虑得分和干预后焦虑得分、护理满意度比较
     干预前对照组和干预组家长焦虑得分差异无统计学意义(P>0.05)。干预后干预组家长术后焦虑得分比对照组家长术后焦虑得分低,差异有统计学意义(P<0.05)。干预后干预组家长护理服务满意度比对照组高,差异有统计学意义(P<0.05)。
     4质性研究提炼出4个主题
     质性研究提炼出护士普遍经历过患儿的疼痛、缺乏疼痛评估量表的使用、护士缺乏疼痛治疗和非药物干预的相关知识、疼痛管理面临多重挑战4个主题。
     结论
     以家庭为中心护理和多种非药物干预相结合的疼痛干预模式,可以降低患儿术后疼痛、焦虑程度及患儿家长的焦虑程度,提高护理服务满意度。
Operation is the only way for Children with Tethered Cord Syndrome. Because the operation is complicated and need long incisions,the patients have significant postoperative pain. It's so important for patients to build postoperative pain intervention model。
     Objective
     To explore the effects of the integrative pain intervention models of family-centered care and multimodal nonpharmacological interventions on postoperative pain and anxiety in infants with tethered cord syndrome, and anxiety, satisfaction with nursing in parents of children with tethered cord syndrome. According to the actual perception of nursing personnel in the management of pediatric pain, to provide effective reference for further development of pain management services.
     Methods
     1Objects
     A quasi-experiment controlled design was employed.20cases of3-12years old children with tethered cord syndrome and their parents in The Third Affiliated Hospital of Zhengzhou University from October,2011to March,2012were selected as control group through convenience sampling.20cases of3-12years old children with tethered cord syndrome and their parents were selected as intervention group from March,2012to December,2012.
     2Methods
     The control group children used the common clinical care model, and their parents acquired convention health and postoperative nursing care education. The intervention group used integrative pain intervention models of family-centered care and multimodal nonpharmacological interventions.The Faces Pain Scale(FPS), The modified Yale Preoperative Anxiety Scale(YPAS), State Anxiety Inventory(SAI), Newcastle Satisfaction with Nursing Scale (NSNS) were used to assess the two groups after the intervention. In-depth interview was conducted on8pediatric nurses adopting qualitative research.
     3Statistics analysis
     SPSS17.0was used to analysis all data. Mean and Std deviation were used to describe the measurement data such as age. Frequency was used to describe the count data such as gender. Significant difference of the measurement data between two groups of children were compared by two independent-sample Mann-Whitney U test and T test. Difference between the count data of the two groups of children were compared by Fisher exact test. Two independent-sample T test were used to compare the difference of anxiety in two sets of parents before the intervention. After intervention, the two groups' scores of FPS, YPAS, SAI and NSNS were analyzed by two independent-sample T test and Mann-Whitney U test. The significant level was a=0.05.
     Results
     1The comparison of indicators between intervention group and control group
     The data of age, age structure, gender, residence and operation time did not differ significantly between the two groups (P>0.05).
     2The comparison of postoperative pain and anxiety in children between intervention group and control group
     1hour and24hour after intervention, pain scores measured in this study were not significantly different (P>0.05).8-16hour after the surgery, the scores of FPS and YPAS were significantly decreased in the intervention group compared with the control group (P<0.05).
     3The comparison of the scores of anxiety and satisfaction with nursing of parents of children with tethered cord syndrome between before and after intervention
     There is no significant difference of the scores of anxiety and of parents between intervention group and control group before intervention (P>0.05).After intervention, the scores of anxiety of parents were decreased in the intervention group compared with the control group (P<0.05). The scores of NSNS were significantly increased in the intervention group compared with the control group (P<0.05).
     4Through this qualitative research,4themes were extracted
     Through this qualitative research,4themes were extracted:common experiences of pain in children, limited knowledge of pain assessment scale, lack of pain treatment knowledge and non-pharmaceutical intervention knowledge, multiple challenges on pain management.
     Conclusions
     The integrative pain intervention models of family-centered care and multimodal non-pharmacological interventions can relief children's postoperative pain and anxiety, alleviate parents' anxiety, improve satisfaction with nursing during their children with tethered cord syndrome were in the hospital.
引文
[1]Tareen B,MemoM, Cerone J, et al. Tethered cord syndrome in a 24 year old woman pesenting with urinary retention[J]. Int U rogynecol JPelvic Floor Dysfunct,2007,18 (6): 679-681.2001:1311.
    [2]肖仁梅,赵洪英.小儿术后疼痛控制及护理进展[J].中国实用护理杂志,2005,21(1):49-50.
    [3]Merskey H, Albe-Fessard DG, Boniea JJ, et al. Pain terms:A list with definition and noteson usage [J].Pain,1979,6:249-252.
    [4]Vanhatalo S, van Nieuwenhuizen O. Fetal pain[J]? Brain Dev,2000,22:145-150
    [5]Johnston CC, Stevens B, Craig KD, et al:Developmental changes in pain expression in premature, full-term two and four-month-old infants[J]. Pain,1993,52:201-208.
    [6]Marc Van de Velde, Jacques Jani, Frederik De Buck, et al. Fetal pain perception and pain management. Fetal and Neonatal Medicine[J],2006,11(4):232-236.
    [7]张冰,张雪华,金元,等.围手术期小儿疼痛阈值的评估及其影响因素分析[J].浙江医学,2011,33(6):868-870.
    [8]Stevens BJ, Abbott LK, Yamada J,et al. Epidemiology and management of painful procedures in children in Canadian hospitals [J]. Canadian Medical Association Journal, 2011,183(7):E403-410.
    [9]Franck LS, Greenberg CS, Stevens B. Pain assessment in infants and children [J]. Pediatric Clinics North Amercia,2000,47 (3):487-512.
    [10]Anand KJ, Barton BA, Mclntosh N, et al. Analgesia and sedation in Preterm neonates who require Ventilatory support[J]. Arehives pediatric and Adolescent Medicine,1999,153(4): 331-338.
    [11]Shrestha—Ranjit JM, Manias E.Pain assessment and management practices in children following surgery of the lower limb[J].Journal of Clinical Nursing,2010.19(1-2):118-128.
    [12]Powers SW. Empirically supported treatments in pediatric psychology:procedure-related pain [J]. Pediatric Psychology,1999,24:131-145.
    [13]Kain ZN, Mayes LC, Caldwell-Andrews AA, et al Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery[J].Pediatrics,2006,118: 651-658.
    [14]Kain ZN, Caldwell-Andrews AA, Mayes LC, et al. Family-centered preparation for surgery improves preoperative outcomes in children:a randomized controlled trial [J]. Anesthesiology,2007,106:65-74.
    [15]Tse MM,Chan MF,Benzie IF.The effect of music therapy on postoperative pain, heart rate,systolic blood pressures and analgesic use following nasal surgery[J]. Journal Pain and Palliative Care Pharmacotherapy,2005,19(3):21-29.
    [16]Gil KM, Edens JL, Wilson JJ, et al. Coping strategies and laboratory pain in children with sickle cell disease[J]. Ann Behav Med,1997,19:22-29.
    [17]Gil KM, Anthony KK, Carson JW, et al. Daily coping practice predicts treatment effects in children with sickle cell disease[J]. Pediatric Psychology,2001,26:163-173.
    [18]Hernandez-Reif M, Field T, Largie S, et al.Children's distress during burn treatment is reduced by massage therapy[J]. Burn Care and Rehabilitation,2001,22(2):191-195.
    [19]Field T, Hernandez-Reif M, Seligman S, et al:Juvenile rheumatoid arthritis:benefits from massage therapy[J]. Pediatric Psychology,1997,22:607-617.
    [20]Bruce B, Letourneau N, Ritchie J, et al. A multisite study of health professionals' perceptions and practices of family-centered care[J]. Family Nursing,2002,8(4):408-429.
    [21]Hutchfield K. Family-centered care:a concept analysis[J]. Advanced Nursing,1999, 29(5):1178-1187.
    [22]Manworren RC. Development and testing of the pediatric nurses'knowledge and attitudes survey regarding pain[J]. Pediatric Nursing,2001,27(2):151-158.
    [23]Caro P,Derevensky JL. Family-Focused Intervention Model Implementationand Research Findings[J]. Top Early Child Spec Edl,1991, 11(3):66-80.
    [24]Gatchel RJ. Clinical essentials of pain management[M]. Washington, DC:American psychological Press,2006,236-237.
    [25]黄科昌,韩伯秀,王玉英,等.医护人员对术痛和术后镇痛态度的调查[J].潍坊医学院学报,2003,25(1):40-42.
    [26]Bruce B, Letourneau N, Ritchie J,et al A Multisite Study of Health Professionals' Perceptions and Practices of Family-entered Care[J]. Journal of family nursing,2002,8(4), 408-429
    [27]Caffery M. Choosing a faces pain scale [J]. Nursing,2002,32 (5):68.
    [28]Kain ZN,Mayes LC,Cicchetti DV,et al.The Yale preoperative anxiety scale:how does it compare with a"gold standard" [J]?Anesthesia and analgesia,1997,85(4):783-788.
    [29]汪向东,王希林,马弘,等.心理卫生评定量表手册(增订版)[M].北京:中国心理卫生杂志社,1999:205-209.
    [30]McColl E,Thomas L,Bond S.A study to determine patoent satisfaction with nursing care[J].Nursing Standard,1996,10:34-38.
    [31]homas LH, McColl E,Priest J,et al. Newcastle satisfaction with nursing scales:an Instrument For Quality Assessments of Nursing Care[J]. Quality in Health Care,1996,5:62-72.
    [32]Kristensson-Hallstrom I.Strategies for feeling secure influence parents' participation in care[J]. Journal of Clinical Nursing,1999,8(5):586-592.
    [33]Yamada S, Lonser RR. Adult tethered cord syndrome [J]. Journal of Spinal Disorders,2000, 13(4):319-323.
    [34]Lambert SA. The effects of hypnosis/guided imagery on the postoperative course of children[J]. Journal of Developmental and Behavioral Pediatrics,1996,17(5),307-310
    [35]Huth MM., Broome ME. Good M. Imagery reduces children's post-operative pain[J]. Pain, 2006,110(1-2),439-448.
    [36]Polkki T, Pietila AM, Vehvilainen-Julkunen K. Imagery-Induced Relaxation in Children's Postoperative Pain Relief:A Randomized Pilot Study[J]. Journal of Pediatric Nursing, 2008,23(3):217-214.
    [37]刘慧莲,刘群,谢红英,等.应用冥想训练减轻心脏病患儿手术后疼痛的效果观察[J].中华护理杂志,2011,46(8):745-747.
    [38]Nilsson U. The Anxiety and Pain Reducing Effects of Music Interventions:A Systematic Review[J]. Aorn Journal,2008,87(4):780-807
    [39]Crowe BJ. Music and Soulmaking:Toward a New Theory of Music Therapy[M]. Lanham, Md:Scarecrow Press,2004.
    [40]魏庆.抚触及穴位按摩对小儿疝气术后疼痛的影响[J].护理研究,2011,25(9):2399-2400.
    [41]Polkki T, Pietila AM, Vehvilainen-Julkunen K,et al.Parental views on participation in their child's pain relief measures and recommendations to health care providers[J]. Journal of Pediatric Nursing,2002,17(4):270-278.
    [42]Palmer SJ. Care of sick children by parents:a meaningful role[J]. Journal of Advanced Nursing,1993,18(2):185-191.
    [43]Leardi S, Pietroletti R, Angeloni G et al. Randomized clinical trial examining the effect of music therapy in stress response to day surgery[J]. journal of surgery2007;94(8):9439-47.
    [44]Nilsson U. The effect of music intervention in stress response to cardiac surgery in a randomized clinical trial. Heart and Lung,2009,38(3):201-207.
    [45]McRee LD; Noble S; Pasvogel A. Using massage and music therapy to improve postoperative outcomes[J]. AORN Journal,2003,78(3):433-442,445-447.
    [46]Bennett-Branson SM,Craig KD. Postoperative pain in children:Developmental and family influences on spontaneous coping strategies. Canadian Journal of Behavioral Sciences[J], 1993,25(3),355-383.
    [47]LaMontagne LL, Hepworth JT., Byington K,et al. Child and parent emotional responses during hospitalization for orthopaedic surgery[J]. American Journal of Maternal Child Nursing,1997,22(6),299-303.
    [48]郝伟.精神病学[M].北京:人民卫生出版社,2002:145.
    [49]叶绿芝,高丽君,汤素华,等.信息支持对围手术期患儿家长焦虑情绪的影响[J].护理研究,2004,18(22):2009-2010.
    [50]Parent N, Fortin F. A randomized, controlled trial of vicarious experience through peer support for male first-time cardiac surgery patients:Impact on anxiety, self-efficacy expectation, and self-reported activity[J]. Heart and Lung:The Journal of Acute and Critical Care,2000,29(6):389-400.
    [51]管咏梅,顾晓蓉,何萍萍.先天性心脏病患儿父母围手术期需求的调查研究[J].中华护理杂志,2008,43(10):938-941.
    [52]Fina DK, Lopas LJ, Stagnone JH,et al. Parent Participation in the Postanesthesia Care Unit:Fourteen Years of Progress at One Hospital[J]. Journal of PeriAnesthesia Nursing, 1997,12(3):152-162.
    [53]Shields L, Kristensson-Hallstrom I. An examination of the needs of parents of hospitalized children:comparing parents'and staffs perceptions[J]. Scandinavian Journal of Caring Sciences,2003,17(2):176-184.
    [54]Sarajarvi A, Haapamaki ML,Paavilainen E.Emotional and informational support for families during their child's illness[J].International Nursing Review,2006,53(3):205-210.
    [55]Hallstrom I,Elander G.Decision—making during hospitalization:Parents'and children's involvement[J].Journal of Clinical Nursing,2004,13(3):367-375.
    [56]Power N, Liossi C, Franck LS. Family-Centered Care[J]. Journal for Specialists in Pediatric Nursing,2007,12(3):203-209.
    [57]楼建华,张玉侠,樊信.儿科护士疼痛知识和应对态度的调查[J].解放军护理杂志,2006,23(9):37-39.
    [58]南华,利民.儿外科护士疼痛知识和态度调查[J].中国医药科学,2012,02(18):130-131.
    [59]喻惠丹,Marcia Petrini,刘义兰,等.护士对老年病人疼痛知识掌握的现状调查及对策[J].中华护理杂志,2006,41(8):696-698.
    [60]李金霞.妇产科病人术后疼痛的评估与护理[J].中国实用护理杂志,2003,19(11):31-32.
    [61]朱音,任丽华.开胸病人疼痛及情绪与护理评估差异的比较[J].护理学杂志,2002,17(9):647-648.
    [62]MacLaren JE,Cohen LL.Teaching behavioral pain managemem to healthcare professionals: a systematic review of research in training programs[J].The Journal of Pain,2005,6(8): 481-492.
    [63]Hunter J,Watt—Watson J,McGillion M, et al.An interfaculty pain curriculum:lessons learned from six years experience[J].Pain,2008,140(1):74-86.
    [64]Watt-Watson J,Hunter J,Pennefather P,et al.An integrated undergraduate pain curriculum, based on IASP curricula,for six health science faculties[J].Pain,2004,110(1-2:140-148.
    [65]庹焱,继军,管孝君.疼痛护理学教学实践与思考[J].现代护理,2002,8(11):861-862.
    [66]林春,何瑞岚,曾真.开设《疼痛学》选修课的实践与认识[J].福建医科大学学报(社会科学版),2005,6(2):42-43.
    [67]郑儒君,符琰,段迎,等.三级甲等医院医务人员疼痛管理影响因素的调查研究[J].护理研究,2012,26(22):2048-2050.
    [68]史艳萍,郑蔚,张利霞,等.护理人员疼痛知识培训效果分析[J].护士进修杂志,201227(15):1358-1360.
    [1]American Academy of Pediatrics,Prevention and management of pain and stress in the neonate[J].Pediatrics,2000,105(2):454-461.
    [2]Gordon DB, Dahl JL, Miaskowski C, et al. American Pain Society recommendations for improving the quality of acute and cancer pain management:American Pain Society Quality of Care Task Force[J]. Archives of Internal Medicine,2005,165(14):1574-1580.
    [3]宋文阁,傅志俭.临床疼痛学[M].第三版.济南:山东科学技术出版社,2004:723-726.
    [4]Haidon JL, Cunliffe M. Analgesia for neonates[J]. Continuing Education in Anaesthesia,2010,10 (4):123-127.
    [5]Johnston CC, Fernandes AM,Campbell-Yeo M. Pain in neonates is different[J]. Pain,2011,152(3):65-73.
    [6]陈梅芳.婴儿和儿童疼痛评估的FLACC量表法[J].国外医学:护理学分册,2003,22(6):289-290.
    [7]Katherine Brand, Colleen Court.Pain assessment in children [J].Anesthesia And Intensive Care Medicine,2010,11(6):214-216
    [8]Bieri D, Reeve RA, Champion GD, et al.The face pain scale for the self assessment of the severity of pain experienced by children:Development, initial validation, and preliminary investigation for the ratio scale properties[J]. Pain,1990,41(2):139-150.
    [9]Wong D, Baker C. Pain in Children:Comparison of assessment scales. Pediatric Nursing. 1988,14(1):9-17.
    [10]Garra G, Singer AJ,Domingo A,et al. The Wong-Baker Pain FACES Scale Measures Pain, Not Fear[J]. Pediatric Emergency Care,2013,29(1):17-20.
    [11]Harrison D, Boyce S, Loughnan P, et al. Skin conductance as a measure of pain and stress in hospitalised infants. Early Human Development 2006,82(9):603-608.
    [12]王芳,岳云.区域神经阻滞对腹股沟疝手术患儿的术后镇痛效果[J].中华麻醉学杂志,2006,26(10):957-958.
    [13]苏涛,何亮,伍湘伊.吗啡用于低龄小儿术后持续静脉镇痛[J].新疆医学,2009,39(10):61-62.
    [14]Kart T, Christrup LL, Rasmussen M. Recommended use of morphine in neonates, infants and children based on a literature review:Part 2--Clinical use [J].Paediatric Anaesthesia, 1997,7(2):93-101
    [15]李晓蓉.吗啡与芬太尼用于小二术后硬膜外镇痛的临床比较[J].齐齐哈尔医学院学报,2012,33(4):477.
    [16]Fredheim OM,Skurtveit S,Moroz A,et al. Prescription pattern of codeine for non-malignant pain:a pharmacoepidemiological study from the Norwegian Prescription Database[J]. Acta Anaesthesiologica Scandinavica,2009,53(5):627-633.
    [17]殷霞丽,马正良.曲马多用于术后镇痛的效果及安全性的Meta分析[J].临床麻醉学杂志,2011,27(10):965-967.
    [18]Southey ER, Soares-Weiser K, Kleijnen J. Systematic review and meta-analysis of the clinical safety and tolerability of ibuprofen compared with paracetamol in paediatric pain and fever[J].. Current Medical Research Opinion,2009,25(9):2207-2222.
    [19]李莉,刘怀萍,陈燕珠.吗啡不同给药途径在小儿术后自控镇痛中的应用[J].河北医学,2008,14(3):301-303.
    [20]李莉,w2忱,刘怀萍.小儿硬膜外注射吗啡术后自控镇痛最佳剂量探讨[J].中国医师进修杂志,2007,30(9):16-20.
    [21]Yaster M. Multimodal analgesia in children[J]. European Journal of Anaesthesiology, 2010,27(10):851-857.
    [22]Mazoit JX. Local anesthetics and their adjuncts[J]. Pediatric Anesthetics, 2012,22(1):31-38.
    [23]White PF. Multimodal analgesia:its role in preventing postoperative pain[J]. Current Opinion Investigational Drugs,2008,9(1):76-82.
    [24]Sandhu T, Paiboonworachat S, Ko-iam W. Effects of preemptive analgesia in laparoscopic cholecystectomy:a double-blind randomized controlled trial [J].Surgical Endoscopy,2011 25(1):23-27.
    [25]叶健鸿,彭俊,杨璐,等.帕瑞昔布钠在腹腔镜胆囊切除术中预先性镇痛的效果[J].实用医学杂志,2011,27(8):1422-1423.
    [26]申林.预先镇痛防治小儿疝气术后疼痛的临床研究[J].山东医药,2008,48(24):105-106.
    [27]Bandstra NF, Skinner L, LeBlanc C, et al. The role of child life in pediatric pain management:a survey of Child Life Specialists[J]..Journal Pain,2008,9(4):320-329.
    [28]刘金娥.非药物性护理干预在治疗儿童疼痛中的应用[J].护理实践与研究,2012,9(17):11-12.
    [29]张玉香,张玉榕,崔立敏,等.护理干预对学龄期儿童肱骨髁上骨折术后疼痛的影响[J].中华现代护理杂志,2011,17(20):2393-2395
    [30]LaMontagne L, Hepworth JT, Salisbury MH, et al.Effects of coping instruction in reducing young adolescents' pain after major spinalsurgery[J]..Orthopaedic Nurses,2003,22(6): 398-403,
    [31]张玉花.心理干预对减轻接种儿童疼痛200例观察分析[J].中国保健营养,2012,22(4):438.
    [32]王薇,王萌萌,林平,等.认知行为干预对学龄前儿童诊疗性疼痛的影响[J].中华现代护理杂志,2011,18(36):4406-4408.
    [33]郭小妹,谢婉花,周英,等.气质和知觉教养方式对儿童OSAHS术后疼痛强度的影响[J].护理学杂志,2011,26(8):4-7.
    [34]Huth MM, Broome ME, Good M. Imagery reduces children's post-operative pain.[J]. Pain,2004,110(1-2):439-448.
    [35]刘慧莲,刘群,谢红英,等.应用冥想训练减轻心脏病患儿手术后疼痛的效果观察[J].中华护理杂志,2011,46(8):745-747.
    [36]Liossi C, Whire P, Hatira P. Randomized clinical trial of local anesthetic versus a combination of local anesthetic with self-hypnosis in the management of pediatric procedure-related pain. [J].Health Psychology,2006,25(3):307-315.
    [37]Schmitt YS, Hoffman HG, Blough DK, et al..A randomized controlled trial of immersive Virtual reality analgesia, during physical therapy for pedialric bums[J]. Bums,2011, 37(1):61-68
    [38]熊晓,菊毛靖.虚拟现实技术在儿童乳牙拔除术中的应用[J].护理学杂志,2012,27(12):47-49.
    [39]Miller K, Rodger S, Bucolo S, et al. Multimodal distraction to relieve pain in children undergoing acute medical procedures[J]. Zhonghua Shao Shang Za Zhi,2009 25(5):352-356.
    [40]Aitken JC, Wilson S, Coury D, et al. The effect of music distraction on pain, anxiety and behavior in pediatric dental patients[J].Pediatric Dentistry,2002,24(2):114-118.
    [41]邱丽萍,张婷婷,黄敏英,音乐疗法对自血病患儿腰椎穿刺术疼痛的影响[J].临床医学工程,2010,17(7):122-123.
    [42]Kain ZN, Mayes LC, Caldwell-Andrews AA, et al. Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery[J]. Pediatrics, 2006,118(2):651-658.
    [43]Polkki T, Vehvilainen-Julkunen K, Pietila AM. Nonpharmacological methods in relieving children's postoperative pain:a survey on hospitalnurses in Finland[J] Journal of Advanced Nursing,2001,34(4):483-492.
    [44]魏庆.抚触及穴位按摩对小儿疝气术后疼痛的影响[J].护理研究,2011,25(9):2399-2400.
    [45]何丽丽,叶福莲,李兰花.会阴侧切术后应用冷热疗法的效果观察及护理[J].当代医学,2012,18(12):124-125.
    [46]Kotani N, Hashimoto H, Sato Y, et al.Preoperative intradermal acupuncture reduces postoperative pain, nausea and vomiting, analgesic requirement,and sympathoadrenal responses[J]. Anesthesiology 2001,95(2):349-356.
    [47]Wang SM, Maranets I, Weinberg ME, et al.Parental auricular acupuncture as an adjunct for parental presence during induction of anesthesia[J]. Anesthesiology,2004,100(6):1399-1404.
    [48]Stephens BK, Barkey ME, Hall HR. Techniques to comfort children during stressful procedures[J]. Accident and emergency nursing,1999,7(4):226-236.
    [49]高杰,周信平,张欣.不同干预方法减轻婴幼儿预防接种注射疼痛的效果[J].解放军护理杂志,2012,29(18):7-9.
    [50]黄少敏,吴寿和,程冬兰,等.新生儿穿刺疼痛缓解方法对比[J].国际医药卫生导报,2012,18(22):3250-3252.