摘要
洁霉素发酵生产是典型的微生物次级代谢过程,生物反应发酵机理复杂,其发酵水平与国际先进水平相比仍有一定的差距。究其原因,除了菌种因素之外,主要是生产的自动化程度不高,控制水平比国外落后。所以,研究基于计算机控制技术的洁霉素发酵过程控制系统,具有重要的现实意义。
本文首先介绍了我国抗生素发酵工业及发酵水平状况,着重分析了抗生素发酵过程控制的研究现状与发展趋势。
其次介绍了洁霉素发酵工艺的过程、发酵过程控制的概念和基本方法,重点分析了发酵过程中的主要发酵参数的控制方法的研究现状。
根据发酵工艺特点和控制要求,提出了一套基于组态王6.5及S7-300PLC的洁霉素发酵过程控制系统的软硬件解决方案。对控制系统的硬件部分进行设计,对控制系统上、下位机的软件功能进行介绍和整体设计规划。
重点对OPC技术及其在洁霉素发酵过程控制系统中的应用进行研究。提出了采用OPC技术实现控制系统的硬件与软件,及软件与软件间的数据通信。详细地论述了OPC服务器和OPC客户端的设计方法及主要实现步骤,并实现了组态王软件与OPC服务器的连接。
针对发酵过程中温度控制具有严重的非线性及滞后性这一难题,本文运用了模糊自适应PID控制,对温度控制环节进行建模并利用MATLAB的simulink进行仿真。
最后,对全文的工作做了总结。总结了主要完成的工作,分析了存在的问题,并对今后的发展方向进行了展望。
本文的主要研究成果为:(1)采用OPC技术实现控制系统的软硬件间的数据通信,并对其中的关键技术OPC服务器进行设计,并且实现了组态王软件与OPC服务器的连接。OPC技术在本控制系统中的应用大大提高了系统的可靠性和扩展的灵活性。(2)基于模糊自适应PID控制算法实现了温度的控制,该控制器具有适应性强、响应迅速,控制效果明显优于常规PID控制方法,适合于发酵过程的温度控制领域以及其他的相关控制领域。
Licomycin fermentation production is the typical microorganism secondary metabolism process, its biological response fermentation mechanism is complex and its fermentation level compared to international advanced level still has certain disparity. Look into the causes, besides the mold mushroom spawn factor, the mainly resaon lies in the fact that the automation degree of the production compared to overseas is not high and its control level falls behind. Therefore, the research on process control system of Licomycin ferentation based on the computer control technology, has important realistic meaning.
Firstly, the paper introduces our country antibiotic fermentation industry and the fermentation level condition, comprehensively analyzes the present situation and development trends about the process control system of antibiotic fermentation.
Secondly, the paper introduces Licomycin fermentation process, concept and basic method of ferment process control, emphasizes the research of present situation based on the control method of the main fermentation parameter.
According to the fermentation process characteristic and the control request, a set of software and hardware solutions for one process control system of Licomycin ferentation based on software kingview 6.5 and Simatic PLC has been proposed and realized. It includes the design of the hardware of the control system, the introduce of the description of the software function for the master and the salve machine ,and the design plan of the Software part.
This paper conducts the research on the OPC technology and its application in the process control system of Licomycin ferentation. It proposes to realize data communication of control system, between hardware and software or between software and software by using OPC technology. It elaborates in detail the design method and the main realization step of OPC server and OPC customer, moreover has realized connection between software kingview and the OPC server.
Aim at the difficult problem that the temperature control has serious nonlinearity and lagging in the fermentation process, this paper has utilized the fuzzy auto-adapted PID control for carrying on the modelling to the temperature control and carried on the simulation by using MATLAB simulink.
Finally, It makes a summary to the full work.It Summaries the work which mainly be complete, danalyzes the existing problem, and carries on the forecast to the next development direction in the future.
The production of the paper follows: (1) The data communication of control system between software and hardware is realized by using the OPC technology, the key technical problem is settled successfully by designing OPC server, moreover it has realized connection between software kingview and the OPC server. (2) The temperature controller is realized based on the fuzzy auto-adapted PID control, which has the strong compatibility and rapid response, and has more obvious effect of control than the conventional PID control method, and suits to the temperature control domain of fermentative process and all that correlation control domains.
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