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在“Elsevier电子期刊”中，命中：585条，耗时：0.041984 秒

在所有数据库中总计命中：738条

1.Selective agonism of mGlu8 receptors by (S)-3,4-dicarboxyphenylglycine does not affect sleep stages in the rat

作者：Marí ; a Cavas ; ^{mcavas@uma.es} ; Gianluigi Scesa ; Mercedes Martí ; n-Ló ; pez ; José ; Francisco Navarro

关键词：Metabotropic glutamate receptors ; mGlu8 ; Sleep ; Slow wave sleep ; REM sleep

刊名：Pharmacological Reports

出版年：2017

2.Metabotropic glutamate receptors and neurodegenerative diseases

作者：Fabiola M. Ribeiro^a ; Luciene B. Vieira^b ; Rita G.W. Pires^c ; Roenick P. Olmo^a ; Stephen S.G. Ferguson^d ; ^{sferguso@uottawa.ca}

关键词：AMPA ; α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid ; Aβ ; amyloid β peptide ; AD ; Alzheimer&rsquo ; s disease ; APP ; amyloid precursor protein ; BDNF ; brain derived neurotrophic factor ; BF ; basal forebrain ; CGA ; chromogranin A ; CNS ; central nervous system ; DAG ; diacylghycerol ; ERK ; extracellular signal-regulated kinase ; GABA ; gamma-aminobutyric acid ; GDNF ; glial cell line-derived neurotrophic factor ; GIRK ; inward rectifying K+ channels ; GP ; globus pallidum ; GPe ; globus pallidum externa ; GPCR ; G

刊名：Pharmacological Research

出版年：2017

3.Blocking metabotropic glutamate receptor subtype 5 relieves maladaptive chronic stress consequences

作者：Daniel Peterlik^a ; Christina Stangl^a ; Amelie Bauer^a ; Anna Bludau^a ; Jana Keller^a ; Dominik Grabski^a ; Tobias Killian^a ; Dominic Schmidt^b ; Franziska Zajicek^a ; Georg Jaeschke^d ; Lothar Lindemann^c ; Stefan O. Reber^e ; Peter J. Flor^a ; ^{peter.flor@ur.de} ; Nicole Uschold-Schmidt^a ; ^{nicole.uschold@ur.de}

关键词：mGlu5 ; Knockout ; CTEP ; Chronic subordinate colony housing ; Chronic psychosocial stress ; Stress-protective phenotype

刊名：Brain, Behavior, and Immunity

出版年：2017

4.Inside story of Group I Metabotropic Glutamate Receptors (mGluRs)

作者：Samarjit Bhattacharyya ^{samarjit@iisermohali.ac.in" class="auth_mail" title="E-mail the corresponding author}

关键词：Endocytosis ; Trafficking ; Desensitization ; Receptor recycling ; GPCR ; Metabotropic glutamate receptors ; Neurotransmitter receptors

刊名：International Journal of Biochemistry and Cell Biology

出版年：2016

5.Inhibition of metabotropic glutamate receptor 1 suppresses tumor growth and angiogenesis in experimental non-small cell lung cancer

作者：Hui Xia^a ; ¹ ; Ying-Nan Zhao^a ; ¹ ; Chang-Hai Yu^a ; Yun-Long Zhao^a ; Yang Liu^b ; ^{xiahui20133@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Metabotropic glutamate receptor 1 ; Non-small cell lung cancer ; Tumor growth ; Angiogenesis

刊名：European Journal of Pharmacology

出版年：2016

6.Synthesis and evaluation of N-(methylthiophenyl)picolinamide derivatives as PET radioligands for metabotropic glutamate receptor subtype 4

作者：Kun-Eek Kil^a ; Pekka Poutiainen^a ; Zhaoda Zhang^a ; Aijun Zhu^a ; Darshini Kuruppu^b ; Shilpa Prabhakar^c ; Ji-Kyung Choi^a ; Bakhos A. Tannous^c ; Anna-Liisa Brownell^a ; ^{abrownell@mgh.harvard.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：PET ; Metabotropic glutamate receptor subtype 4 (mGlu4) ; Positive allosteric modulator (PAM)

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

7.N-Alkylpyrido[1‿2‿1,5]pyrazolo-[4,3-d]pyrimidin-4-amines: A new series of negative allosteric modulators of mGlu_1/5 with CNS exposure in rodents

作者：Andrew S. Felts^a ; ^b ; Alice L. Rodriguez^a ; ^b ; Ryan D. Morrison^a ; ^b ; Daryl F. Venable^a ; ^b ; Anna L. Blobaum^a ; ^b ; Frank W. Byers^a ; ^b ; J. Scott Daniels^a ; ^b ; Colleen M. Niswender^a ; ^b ; Carrie K. Jones^a ; ^b ; P. Jeffrey Conn^a ; ^b ; Craig W. Lindsley^a ; ^b ; ^c ; Kyle A. Emmitte^a ; ^b ; ^c ; ^{kyle.emmitte@unthsc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Metabotropic glutamate receptor subtype 1 (mGlu1) ; Metabotropic glutamate receptor subtype 5 (mGlu5) ; Negative allosteric modulator (NAM) ; Central nervous system (CNS) ; G-protein coupled receptor (GPCR)

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

8.Discovery of 3-aminopicolinamides as metabotropic glutamate receptor subtype 4 (mGlu4) positive allosteric modulator warheads engendering CNS exposure and in vivo efficacy

作者：Rocco D. Gogliotti^a ; Darren W. Engers^a ; ^b ; Pedro M. Garcia-Barrantes^a ; Joseph D. Panarese^a ; Patrick R. Gentry^a ; Anna L. Blobaum^a ; ^b ; Ryan D. Morrison^a ; J. Scott Daniels^a ; ^b ; Analisa D. Thompson^a ; Carrie K. Jones^a ; ^b ; ^d ; P. Jeffrey Conn^a ; ^b ; ^d ; Colleen M. Niswender^a ; ^b ; ^d ; Craig W. Lindsley^a ; ^b ; ^c ; ^{craig.lindsley@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author} ; Corey R. Hopkins^a ; ^b ; ^c ; ^{corey.hopkins@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：mGlu4 ; Metabotropic glutamate receptor ; Positive allosteric modulator (PAM) ; Parkinson&rsquo ; s disease ; Structure&ndash ; activity relationship (SAR)

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

9.Radiosynthesis and evaluation of 5-methyl-N-(4-[¹¹C]methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine ([¹¹C]ADX88178) as a novel radioligand for imaging of metabotropic glutamate receptor subtype 4 (mGluR4)

作者：Masayuki Fujinaga^a ; ^&dagger ; ; Tomoteru Yamasaki^a ; ^&dagger ; ; Nobuki Nengaki^a ; ^b ; Masanao Ogawa^a ; ^b ; Katsushi Kumata^a ; Yoko Shimoda^a ; Joji Yui^a ; Lin Xie^a ; Yiding Zhang^a ; Kazunori Kawamura^a ; Ming-Rong Zhang^a ; ^{zhang@nirs.go.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：mGluR4 ; PET ; Autoradiography ; [11C]ADX88178

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

10.Metabotropic glutamate receptors as targets for new antipsychotic drugs: Historical perspective and critical comparative assessment

作者：Joanna M. Wierońska^a ; Stevin H. Zorn^b ; Dario Doller^b ; Andrzej Pilc^a ; ^{nfpilc@cyf-kr.edu.pl" class="auth_mail" title="E-mail the corresponding author}

关键词：ACPT-I ; (1S ; 3R ; 4S)-1-Aminocyclopentane-13 ; 4-tricarboxylic acid ; ADX ; addex ; AMN082 ; N ; N&prime ; -Bis(diphenylmethyl)-1 ; 2-ethanediamine dihydrochloride ; L-AP-4 ; L-(+)-2-Amino-4-phosphonobutyric acid ; AMP ; amphetamine ; APO ; apomorphine ; BINA ; Biphenyl-indanone A ; CAR ; conditioned avoidance reaction ; CDPPB ; 3-Cyano-N-(1 ; 3-diphenyl-1H-pyrazol-5-yl)benzamide ; CFMTI ; 2-cyclopropyl-5-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-12 ; 3-triazol-4-yl]-2 ; 3-dihydro-1H-isoindol-1-one ; CNS ; central nervous system ; CSF

刊名：Pharmacology and Therapeutics

出版年：2016

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