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在“Elsevier电子期刊”中，命中：3,135条，耗时：0.0959549 秒

在所有数据库中总计命中：4,075条

1.Senescence as biologic endpoint following pharmacological targeting of receptor tyrosine kinases in cancer

作者：Paola Francica ; Daniel M. Aebersold ; Michaela Medová ; ; ^{michaela.medova@dkf.unibe.ch}

关键词：ATIR ; anti-tumor immune response ; ATM ; ataxia telangiectasia mutated ; CDK ; cyclin-dependent kinase ; CGH ; comparative genomic hybridization ; CHK1 ; checkpoint kinase 1 ; CHK2 ; checkpoint kinase 2 ; DDAs ; DNA-damaging agents ; DDR ; DNA damage response ; DSBs ; double-strand breaks ; EGF ; epidermal growth factor ; EGFR ; epidermal growth factor receptor ; EPHA3 ; EPH Receptor A3 ; FGFR ; fibroblast growth factor receptor ; FOXM1 ; Forkhead box protein M1 ; GAS6 ; growth arrest-specific protein 6 ; H3K9me3 ; histone 3

刊名：Biochemical Pharmacology

出版年：2017

2.Cellular responses to replication stress: Implications in cancer biology and therapy

作者：Hui-Ju Hsieh ; ^{hhsieh@mdanderson.org} ; Guang Peng

关键词：53BP1 ; tumor protein p53 binding protein 1 ; 9-1-1 ; RAD9-RAD1-HUS1 ; AND1 ; acidic nucleoplasmic DNA-binding protein 1 ; ATR ; ataxia telangiectasia and Rad3 related ; ATRIP ; ATR interacting protein ; BIR ; break-induced replication ; BLM (RECQL3) ; Bloom Syndrome ; CDC6/7/45 ; cell division cycle 6/7/45 ; CDK1/2/4/6/7 ; cyclin-dependent kinase 1/2/4/6/7 ; CDT1 ; chromatin licensing and DNA replication factor 1 ; CFSs ; common fragile sites ; CHK1/2 ; checkpoint kinase 1/2 ; CMG ; CDC45-MCM-GINS ; CTIP ; CTBP-interacti

刊名：DNA Repair

出版年：2017

3.Caloric restriction - A promising anti-cancer approach: From molecular mechanisms to clinical trials

作者：Gelina S. Kopeina^a ; Vyacheslav V. Senichkin^a ; Boris Zhivotovsky^a ; ^b ; ^{Boris.Zhivotovsky@ki.se}

关键词：Acetyl-CoA/CoA ; acetyl-coenzyme A/Coenzyme A ratio ; AMPK ; AMP-dependent kinase ; APL ; autophagolysosome ; ATG ; autophagy-related gene ; ATP/ADP ; adenosine triphosphate/adenosine diphosphate ratio ; CDK ; cyclin-dependent kinase ; CR ; caloric restriction ; CRM ; caloric restriction mimetics ; DDA ; DNA-damaging agent ; DSR ; differential stress resistance ; EMA ; the European Medicines Agency ; ER ; endoplasmic reticulum ; Erk 1/2 ; extracellular signal&ndash ; regulated kinases 1/2 ; FDA ; Food and Drug Administratio

刊名：Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

出版年：2017

4.Microbiota as a mediator of cancer progression and therapy

作者：Jillian L. Pope^a ; Sarah Tomkovich^a ; ^b ; Ye Yang^a ; Christian Jobin^a ; ^c ; ^{christian.jobin@medicine.ufl.edu}

关键词：AOM ; azoxymethane ; Apc ; adenomatous polyposis coli ; CAC ; colitis associated cancer ; CRC ; colorectal cancer ; DNA-PK ; DNA-dependent protein kinase ; GF ; germ free ; GI ; gastrointestinal ; IBD ; inflammatory bowel diseases ; IL ; interleukin ; MAIT ; mucosa-associated invariant T ; MTX ; methotrexate ; NLR ; NOD-like receptor ; NLRP1 ; NLR family ; pyrin domain containing 1 ; NOD ; nucleotide-binding oligomerization domain-containing protein ; PDL-1 ; programmed cell death protein 1 ligand 1 ; PI3K ; phosphoinositide 3

刊名：Translational Research

出版年：2017

5.Perturbation of genome integrity to fight pathogenic microorganisms

作者：Kinga Nyí ; ri ; ^{nyiri.kinga@ttk.mta.hu} ; Beá ; ta G. Vé ; rtessy ; ^{vertessy@mail.bme.hu}

关键词：CH2THF ; 5 ; 10-methylene tetrahydrofolate ; DCD ; dCTP deaminase ; DCD-DUT ; bifunctional dCTP deaminase&ndash ; dUTPase ; DUT ; dUTPase ; DHF ; dihydrofolate ; DHFR ; dihydrofolate reductase ; DHFR&ndash ; TS ; bifunctional dihydrofolate reductase &ndash ; thymidylate synthase ; FAD ; flavin adenine dinucleotide ; SHMT ; serine hydroxymethyltransferase ; THF ; tetrahydrofolate ; TK ; thymidine kinase ; TS ; ThyX ; classical and flavin-dependent thymidylate synthase ; TMPK ; dTMP kinase ; Ugi ; uracil-DNA glycosylase inhibitor

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2017

6.Reelin expression is up-regulated in mice colon in response to acute colitis and provides resistance against colitis

作者：Ana E. Carvajal ; Marí ; a D. Vá ; zquez-Carretero ; Pablo Garcí ; a-Miranda ; Marí ; a J. Peral ; Marí ; a L. Calonge ; ^{calonge@us.es} ; Anunciació ; n A. Ilundain

关键词：α-SMA ; α-smooth muscle actin ; ApoER2 ; apolipoprotein E receptor 2 ; CASK ; calcium/calmodulin-dependent serine protein kinase ; Dab1 ; Disabled-1 ; DSS ; dextran sulphate sodium ; DNMT1 ; (DNA (Cytosine-5-)-Methyltransferase 1) ; IL-1β ; interleukin-1β ; PDGF-BB ; platelet derived growth factor β ; TGF-β1 ; transforming growth factor β1 ; TNF-α ; tumour necrosis factor α ; Sp1 ; transcription factor Sp1 ; Tbr1 ; T-box brain 1 ; VLDLR ; very low-density lipoprotein receptor

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

7.In-silico screening for DNA-dependent protein kinase (DNA-PK) inhibitors: Combined homology modeling, docking, molecular dynamic study followed by biological investigation

作者：Hamadeh Tarazi^a ; ^b ; ^{htarazi@sharjah.ac.ae" class="auth_mail" title="E-mail the corresponding author} ; Ekram Saleh^b ; ^c ; Raafat El-Awady^a ; ^b

关键词：DNA-PK ; Homology modeling ; Virtual screening ; Molecular dynamic

刊名：Biomedicine & Pharmacotherapy

出版年：2016

8.DNA-PKcs: A promising therapeutic target in human hepatocellular carcinoma?

作者：Rosa M. Pascale^a ; ¹ ; Christy Joseph^b ; ¹ ; Gavinella Latte^a ; Matthias Evert^c ; Francesco Feo^a ; Diego F. Calvisi^a ; ^b ; ^{calvisid@uniss.it" class="auth_mail" title="E-mail the corresponding author}

关键词：CHIP ; chromatin immunoprecipitation ; DNA-PKcs ; DNA dependent protein kinase catalytic subunit ; DSBs ; double strand breaks ; GI ; genomic instability ; HCC ; hepatocellular carcinoma ; NHEJ ; non-homologous end-joining

刊名：DNA Repair

出版年：2016

9.Lovastatin protects keratinocytes from DNA damage-related pro-apoptotic stress responses stimulated by anticancer therapeutics

作者：Verena Ziegler¹ ; Anne Albers¹ ; Gerhard Fritz ; ^{fritz@uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author}

关键词：53BP1 ; tumor suppressor p53 binding protein 1 ; ATM ; ataxia telangiectasia mutated ; ATR ; ataxia telangiectasia and Rad3-related ; Chk ; checkpoint kinase ; DSB ; DNA double-strand break ; DDR ; DNA damage response ; DNA-PKcs ; DNA-dependent protein kinase ; catalytic subunit ; Doxo ; doxorubicin ; 5-FU ; 5-fluorouracil ; γH2AX ; Ser139 phosphorylated histone H2AX ; HU ; hydroxyurea ; IR ; ionizing radiation ; JNK ; c-Jun N-terminal kinase ; Kap1 ; KRAB-associated protein 1 ; Lova ; HMG-CoA-reductase inhibitor lovastatin

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

10.An Mcm10 Mutant Defective in ssDNA Binding Shows Defects in DNA Replication Initiation

作者：Patricia Perez-Arnaiz¹ ; Daniel L. Kaplan ; ^{Daniel.Kaplan@med.fsu.edu" class="auth_mail" title="E-mail the corresponding author} ; ^{daniel_l_kaplan@yahoo.com" class="auth_mail" title="E-mail the corresponding author}

关键词：GINS ; Go ; Ichi ; Ni ; and San ; CMG ; Cdc45 ; the heterohexameric Mcm2&ndash ; 7 complex ; and the tetrameric GINS ; CDK ; cyclin-dependent kinase ; DDK ; Dbf4-dependent kinase ; dsDNA ; double-stranded DNA ; ssDNA ; single-stranded DNA ; ID ; internal domain ; RPA ; replication protein A ; ChIP ; chromatin immunoprecipitation ; GST ; glutathione S-transferase ; IAA ; indole-3-acetic ; FACS ; fluorescence-activated cell sorting ; PKA ; protein kinase A ; ORC ; origin recognition complex ; BSA ; bovine serum albumin

刊名：Journal of Molecular Biology

出版年：2016

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