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在“Elsevier电子期刊”中，命中：54条，耗时：小于0.01 秒

在所有数据库中总计命中：72条

1.Reduced cardiolipin content decreases respiratory chain capacities and increases ATP synthesis yield in the human HepaRG cells

关键词：Cardiolipin synthase ; Mitochondrial network ; Supercomplexes ; Oxidative phosphorylation ; Hepatocytes

刊名：Biochimica et Biophysica Acta (BBA) - Bioenergetics

出版年：2016

2.Modulation of CYP3A4 activity alters the cytotoxicity of lipophilic phycotoxins in human hepatic HepaRG cells

作者：P.J. Ferron^a ; ^{pierre-jean.ferron@anses.fr" class="auth_mail" title="E-mail the corresponding author} ; K. Hogeveen^a ; G. De Sousa^b ; R. Rahmani^b ; E. Dubreil^c ; V. Fessard^a ; L. Le Hegarat^a

关键词：Phycotoxins ; Hepatocytes ; High content analysis ; CYP3A4 ; Cytotoxicity

刊名：Toxicology in Vitro

出版年：2016

3.Differential sensitivity of metabolically competent and non-competent HepaRG cells to apoptosis induced by diclofenac combined or not with TNF-α

作者：Houssein Al-Attrache^a ; ^b ; ^d ; Ahmad Sharanek^a ; ^b ; Audrey Burban^a ; ^b ; Matthew Burbank^a ; ^b ; Thomas Gicquel^a ; ^b ; ^c ; Ziad Abdel-Razzak^d ; Christiane Guguen-Guillouzo^a ; ^b ; Isabelle Morel^a ; ^b ; ^c ; André ; Guillouzo^a ; ^b ; ^{Andre.Guillouzo@univ-rennes1.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：ABT ; 1-aminobenzotriazole ; Ac-DEVD-AMC ; N-acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin ; AC-IETD-AMC ; Ac-Ile-Glu-Thr-Asp-7-amino-4-methylcoumarin ; AC-LEHD-AMC ; Ac-Leu-Glu-His-Asp-7-Amino-4-methylcoumarin ; BSEP ; bile salt export pump ; CDF ; 5 (and 6)-carboxy-2&prime ; 7&prime ; -dichlorofluorescein (CDF) ; CRP ; C-reactive protein ; CYP ; cytochrome P450 ; DCF ; diclofenac ; DMSO ; dimethyl sulfoxide ; ER ; endoplasmic reticulum ; H2-DCFDA ; 2&prime ; 7&prime ; -dichlorodihydrofluorescein ; HO1 ; heme oxygenase 1

刊名：Toxicology Letters

出版年：2016

4.Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response

作者：Thomas Lahlali¹ ; Marie-Laure Plissonnier¹ ; Cristina Romero-Ló ; pez² ; Maud Michelet¹ ; Benjamin Ducarouge³ ; Alfredo Berzal-Herranz² ; Fabien Zoulim¹ ; Patrick Mehlen³ ; Romain Parent¹ ; ^{romain.parent@inserm.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：Netrin ; UPR ; Hepatocyte ; Translation

刊名：CMGH Cellular and Molecular Gastroenterology and Hepatology

出版年：2016

5.MicroRNA hsa-miR-25-3p suppresses the expression and drug induction of CYP2B6 in human hepatocytes

作者：Yaqiong Jin^a ; ¹ ; Dianke Yu^b ; ¹ ; ^{dianke.yu@fda.hhs.gov" class="auth_mail" title="E-mail the corresponding author} ; William H. Tolleson^b ; Bridgett Knox^b ; Yong Wang^b ; Si Chen^b ; Zhen Ren^b ; Helen Deng^c ; Yongli Guo^a ; ^{guoyongli@bch.com.cn" class="auth_mail" title="E-mail the corresponding author} ; Baitang Ning^b ; ^{baitang.ning@fda.hhs.gov" class="auth_mail" title="E-mail the corresponding author}

关键词：CYP ; cytochrome P450 ; miRNA ; microRNA ; DMETs ; drug metabolizing enzymes and transporters ; CAR ; constitutive androstane receptor ; PXR ; pregnane X receptor ; RE ; response element ; 3&prime ; -UTR ; 3&prime ; -untranslated region ; SULT ; sulfotransferase ; Ago ; argonaute RISC catalytic component ; RISC ; RNA-induced silencing complex ; FBS ; fetal bovine serum ; EMSA ; electrophoretic mobility shift assay

刊名：Biochemical Pharmacology

出版年：2016

6.Drug biokinetic and toxicity assessments in rat and human primary hepatocytes and HepaRG cells within the EU-funded Predict-IV project

作者：Stefan O. Mueller^a ; ^b ; ^{Stefan_otto.mueller@sandoz.com" class="auth_mail" title="E-mail the corresponding author} ; André ; Guillouzo^c ; Philip G. Hewitt^a ; Lysiane Richert^d ; ^e

关键词：AMI ; amiodarone ; ADR ; adverse drug reaction ; CPZ ; chlorpromazine ; CsA ; cyclosporine A ; CYP ; cytochrome P450-dependent monooxygenases ; DICI ; Drug Induced Cholestasis Index ; DILI ; drug-induced liver injury ; DME ; drug metabolizing enzyme ; IBU ; ibuprofen ; NSAID ; non-steroidal anti-inflammatory drug ; PHH ; primary human hepatocytes ; PRH ; primary rat hepatocytes

刊名：Toxicology in Vitro

出版年：2015

7.Experimental in vitro and in vivo models for the study of human hepatitis B virus infection

作者：Lena Allweiss¹ ; Maura Dandri¹ ; ² ; ^{m.dandri@uke.de" class="auth_mail" title="E-mail the corresponding author}

关键词：HBV ; hepatitis B virus ; HCC ; hepatocellular carcinoma ; cccDNA ; covalently closed circular DNA ; PHH ; primary human hepatocytes ; HCV ; hepatitis C virus ; dHepaRG ; differentiated HepaRG ; HDV ; hepatitis Delta virus ; IFN ; interferon

刊名：Journal of Hepatology

出版年：2016

8.Toxicogenomics-based prediction of acetaminophen-induced liver injury using human hepatic cell systems

作者：Robim M. Rodrigues^a ; ^{robim.marcelino.rodrigues@vub.ac.be" class="auth_mail" title="E-mail the corresponding author} ; Anja Heymans^a ; Veerle De Boe^b ; Agapios Sachinidis^c ; Umesh Chaudhari^c ; Olivier Govaere^d ; Tania Roskams^d ; Tamara Vanhaecke^a ; Vera Rogiers^a ; ¹ ; Joery De Kock^a ; ¹

关键词：ALF ; acute liver failure ; APAP ; N-acetyl-p-aminophenol/acetaminophen/paracetamol ; DILI ; drug-induced liver injury ; ESC ; embryonic stem cells ; hHEP ; primary human hepatocytes ; hSKP ; human skin-derived precursors ; hSKP-HPC ; hSKP-derived hepatic progenitor cells ; IPA ; Ingenuity Pathways Analysis ; iPSC ; induced pluripotent stem cells ; NAPQ ; N-acetyl-p-benzoquinoneimine ; NCE ; new chemical entities

刊名：Toxicology Letters

出版年：2016

9.Human arylacetamide deacetylase hydrolyzes ketoconazole to trigger hepatocellular toxicity

作者：Tatsuki Fukami ; ^{tatsuki@p.kanazawa-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Azumi Iida ; Keigo Konishi ; Miki Nakajima

关键词：AADAC ; arylacetamide deacetylase ; BNPP ; bis-(p-nitrophenyl) phosphate ; CES ; carboxylesterase ; DFP ; diisopropyl fluorophosphate ; DMSO ; dimethyl sulfoxide ; G6P ; glucose 6-phosphate ; G6PDH ; glucose 6-phosphate dehydrogenase ; HLM ; human liver microsome ; HPLC ; high-performance liquid chromatography ; KC ; ketoconazole ; LC&ndash ; MS/MS ; liquid chromatography&ndash ; tandem mass spectrometry ; LDH ; lactate dehydrogenase ; MRM ; multiple-reaction monitoring ; NADPH-GS ; nicotine adenine dinucleotide phosphate-gen

刊名：Biochemical Pharmacology

出版年：2016

10.Engineering EMT using 3D micro-scaffold to promote hepatic functions for drug hepatotoxicity evaluation

作者：Jingyu Wang^a ; Fengling Chen^b ; Longwei Liu^c ; Chunxiao Qi^a ; Bingjie Wang^c ; Xiaojun Yan^a ; Chenyu Huang^d ; Wei Hou^e ; Michael Q. Zhang^b ; Yang Chen^b ; ^{yc@tsinghua.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Yanan Du^a ; ^f ; ^{duyanan@tsinghua.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：EMT ; 3D micro-scaffold ; Hepatic functions ; HDACs ; Drug hepatotoxicity evaluation

刊名：Biomaterials

出版年：2016

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