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在“Elsevier电子期刊”中，命中：1,395条，耗时：0.0749653 秒

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1.Ganglioside GM3 Mediates Glucose-Induced Suppression of IGF-1 Receptor-Rac1 Activation to Inhibit Keratinocyte Motility

作者：Duncan Hieu M. Dam¹ ; ² ; Xiao-Qi Wang¹ ; ² ; Sarah Sheu¹ ; Mahima Vijay¹ ; Desmond Shipp¹ ; Luke Miller¹ ; Amy S. Paller¹ ; ^{apaller@northwestern.edu}

关键词：AS ; antisense oligonucleotide ; GCS ; glucosylceramide synthase ; GCSI ; glucosylceramide synthase inhibitor ; GM3S ; ganglioside GM3 synthase ; IGF-1 ; insulin-like growth factor-1 ; IGF1R ; insulin-like growth factor-1 receptor ; IR ; insulin receptor ; M2D3 ; GM2/GD2 and GD3 synthases ; NHEK ; normal human epidermal keratinocyte ; shRNA ; short hairpin RNA ; siRNA ; small interfering RNA ; SNA ; spherical nucleic acid

刊名：Journal of Investigative Dermatology

出版年：2017

2.Epigallocatechin-3-gallate inhibits adipogenesis through down-regulation of PPARγ and FAS expression mediated by PI3K-AKT signaling in 3T3-L1 cells

作者：Mengqing Wu^a ; ^b ; ¹ ; Dan Liu^a ; ^b ; ¹ ; Rong Zeng^a ; ^b ; ¹ ; Tao Xian^a ; ^b ; Yi Lu^a ; ^b ; Guohua Zeng^a ; ^b ; Zhangzetian Sun^c ; Bowei Huang^c ; Qiren Huang^a ; ^b ; ^{qrhuang@ncu.edu.cn}

关键词：4E-BP1 ; 4E-binding protein1 ; C/EBP ; CCAAT/ enhancer binding proteins ; EGCG ; epigallocatechin-3-gallate ; FAS ; fatty acid synthase ; FOXO1 ; forkhead box-O1 ; HFD ; high fat diet ; IGF ; insulin-like growth factor ; IR ; insulin resistance ; IRS1 ; insulin receptor substrate 1 ; MSCs ; mesenchymal stem cells ; PGC1 ; PPARγ coactivator 1 ; PI3K ; phosphatidylinositol 3 kinase ; PPARγ ; peroxisome proliferator activated receptor γ ; Rb ; retinoblastoma protein ; TG ; triglyceride ; TIF2 ; transcriptional intermediary facto

刊名：European Journal of Pharmacology

出版年：2017

3.Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment

作者：Katarzyna Głombik ; Joanna Ślusarczyk ; Ewa Trojan ; Katarzyna Chamera ; Bogusława Budziszewska ; Władysław Lasoń ; Agnieszka Basta-Kaim ; ^{basta@if-pan.krakow.pl}

关键词：Insulin ; Insulin receptor ; Prenatal stress ; Antidepressant drugs ; Brain

刊名：European Neuropsychopharmacology

出版年：2017

4.Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non-Small-Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations

作者：Natasha B. Leighl¹ ; Naiyer A. Rizvi² ; Lopes Gilberto de Lima Jr.³ ; ⁴ ; Wichit Arpornwirat⁵ ; Charles M. Rudin⁶ ; Alberto A. Chiappori⁷ ; Myung-Ju Ahn⁸ ; Laura Q.M. Chow⁹ ; Lyudmila Bazhenova¹⁰ ; Arunee Dechaphunkul¹¹ ; Patrapim Sunpaweravong¹² ; Keith Eaton¹³ ; ¹⁴ ; Jihong Chen¹⁵ ; Sonja Medley¹⁵ ; Srinivasu Poondru¹⁵ ; Margaret Singh¹⁵ ; Joyce Steinberg¹⁵ ; Rosalyn A. Juergens¹⁶ ; ^{juergensr@hhsc.ca} ; Shirish M. Gadgeel¹⁷ ; ¹⁸

关键词：Combination ; Epidermal growth factor receptor inhibitor ; First-line therapy ; Insulin-like growth factor-1 inhibitor ; Tyrosine kinase inhibitor

刊名：Clinical Lung Cancer

出版年：2017

5.Activation of the Tor/Myc signaling axis in intestinal stem and progenitor cells affects longevity, stress resistance and metabolism in drosophila

作者：Olha M. Strilbytska^a ; Uliana V. Semaniuk^a ; Kenneth B. Storey^b ; Bruce A. Edgar^c ; Oleh V. Lushchak^a ; ^{olehl@pu.if.ua}

关键词：AKH ; adipokinetic hormone ; CAFE ; capillary feeding assay ; DILP ; Drosophila insulin-like peptide ; EB ; enteroblast ; EC ; enterocyte ; EE ; enteroendocrine cell ; EGFR ; epidermal growth factor receptor ; ISC ; intestinal stem cell ; JAK/STAT ; Janus kinase and signal transducer and activator of transcription ; PEPCK ; phosphoenolpyruvate carboxykinase ; ROS ; reactive oxygen species ; Su(H) ; suppressor of hairless ; S6K ; kinase of S6 protein ; TAG ; triglycerides ; TOR ; target of rapamycin ; TSC ; tuberous sclerosis

刊名：Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

出版年：2017

6.Deletion of liver-specific STAT5 gene alters the expression of bile acid metabolism genes and reduces liver damage in lithogenic diet-fed mice

作者：Myunggi Baik^a ; ^b ; ¹ ; ^{mgbaik@snu.ac.kr} ; ^{mgbaik2164@naver.com} ; Jangseon Kim^c ; ¹ ; Min Yu Piao^a ; Hyeok Joong Kang^a ; Seung Ju Park^a ; Sang Weon Na^a ; Sung-Hoon Ahn^d ; Jae-Hyuk Lee^e

关键词：STAT5 ; signal transducer and activator of transcription 5 ; GH ; growth hormone ; IGF-1 ; insulin-like growth factor-1 ; LDLR ; low-density lipoprotein receptor ; STAT5 LKO ; liver-specific STAT5 knock-out ; STAT5 fl/fl ; STAT5 flox/flox ; TG ; triacylglycerol ; ChMCs ; cholesterol monohydrate crystals ; H&E ; hematoxylin and eosin ; ORO ; Oil-Red O ; CA ; cholic acid ; CDCA ; chenodeoxycholic acid ; DCA ; deoxycholic acid ; TCA ; taurocholic acid ; TCDCA ; tauro chenodeoxycholic acid ; TDCA ; taurodeoxycholic acid ; GCA ; gly

刊名：The Journal of Nutritional Biochemistry

出版年：2017

7.Insulin-Like Growth Factor Binding Protein-3 Deficiency Leads to Behavior Impairment with Monoaminergic and Synaptic Dysfunction

作者：Hongmei Dai ; Yu-ichi Goto ; Masayuki Itoh ; ^{itoh@ncnp.go.jp}

刊名：The American Journal of Pathology

出版年：2017

8.Differential response to intrahippocampal interleukin-4/interleukin-13 in aged and exercise mice

作者：Alyssa Littlefield^a ; ^b ; ^{alyssa.littlefield@my.rfums.org} ; Rachel A. Kohman^a ; ^{kohmanr@uncw.edu}

关键词：Arg1 ; Arginase-1 ; BDNF ; brain derived neurotrophic factor ; Fizz1 ; found in inflammatory zone 1 ; IGF ; insulin-like growth factor ; IL ; interleukin ; IL-1ra ; IL-1 receptor antagonist ; LPS ; lipopolysaccharide ; PBS ; phosphate-buffered saline ; RT-PCR ; real-time polymerase chain reaction ; s.c. ; subcutaneous ; SEM ; standard error of the mean ; SOCS ; suppressor of cytokine signaling ; TBI ; traumatic brain injury ; TGF-β ; transforming growth factor-β ; TNF ; tumor necrosis factor ; Ym1 ; chitinase-like 3

刊名：Neuroscience

出版年：2017

9.Proinsulin C-peptide modulates the expression of ERK1/2, type I collagen and RANKL in human osteoblast-like cells (Saos-2)

作者：Cristina Russo^a ; Veronica Lazzaro^b ; Carmine Gazzaruso^c ; Samantha Maurotti^a ; Yvelise Ferro^a ; Piero Pingitore^d ; Francesca Fumo^a ; Adriana Coppola^c ; Pietro Gallotti^c ; Valentina Zambianchi^c ; Mariangela Fodaro^c ; Emanuela Galliera^e ; Monica Gioia Marazzi^f ; Massimiliano Marco Corsi Romanelli^f ; Sandro Giannini^g ; Stefano Romeo^a ; ^d ; Arturo Pujia^a ; Tiziana Montalcini^h ; ¹ ; ^{tmontalcini@unicz.it}

关键词：Proinsulin C-peptide ; Insulin ; Osteoporosis ; Type I collagen ; RANKL

刊名：Molecular and Cellular Endocrinology

出版年：2017

10.Insulin-like growth factor 1 (IGF1) affects proliferation and differentiation and wound healing processes in an inflammatory environment with p38 controlling early osteoblast differentiation in periodontal ligament cells

作者：Jan Reckenbeil^a ; ^b ; ^c ; ^d ; ¹ ; Dominik Kraus^a ; ¹ ; Helmut Stark^a ; Birgit Rath-Deschner^b ; Andreas Jä ; ger^b ; Matthias Wenghoefer^d ; Jochen Winter^c ; ¹ ; ^{jochen.winter@ukb.uni-bonn.de} ; Werner Gö ; tz^b ; ¹

关键词：IGF-1 ; IL-1β ; p38 ; Biomineralization ; Inflammation

刊名：Archives of Oral Biology

出版年：2017

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