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在“Elsevier电子期刊”中，命中：2,576条，耗时：0.1209452 秒

在所有数据库中总计命中：3,594条

1.Agastache rugosa Kuntze extract, containing the active component rosmarinic acid, prevents atherosclerosis through up-regulation of the cyclin-dependent kinase inhibitors p21^WAF1/CIP1 and p27^KIP1

作者：Jung-Jin Lee^a ; ^{mhjj3998@kiom.re.kr} ; Ji-Hye Lee^a ; ^{ideal0723@kiom.re.kr} ; Min Jung Gu^a ; ^{guminjung@kiom.re.kr} ; Joo-Hui Han^b ; ^{han5621@cnu.ac.kr} ; Won-Kyung Cho^a ; ^{wkcho@kiom.re.kr} ; Jin Yeul Ma^a ; ^{jyma@kiom.re.kr}

关键词：AKT ; phosphatidylinositol 3-kinase-linked protein kinase ; A.rugose ; Agastacherugosa Kuntze ; BrdU ; bromodeoxyuridine ; CA ; caffeic acid ; CCK-8 ; cell counting Kit-8 ; CDK ; cyclin-dependent kinase ; CKI ; cyclin-dependent kinase inhibitor ; DAD ; diode array UV/VIS detector ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; ERK ; extracellular signal regulated kinase 1/2 ; FBS ; fetal bovine serum ; HPLC ; high-performance liquid chromatographic ; JNK ; c-Jun N-terminal kinase ; PBS ; phosphate-buffered salin

刊名：Journal of Functional Foods

出版年：2017

2.Cellular responses to replication stress: Implications in cancer biology and therapy

作者：Hui-Ju Hsieh ; ^{hhsieh@mdanderson.org} ; Guang Peng

关键词：53BP1 ; tumor protein p53 binding protein 1 ; 9-1-1 ; RAD9-RAD1-HUS1 ; AND1 ; acidic nucleoplasmic DNA-binding protein 1 ; ATR ; ataxia telangiectasia and Rad3 related ; ATRIP ; ATR interacting protein ; BIR ; break-induced replication ; BLM (RECQL3) ; Bloom Syndrome ; CDC6/7/45 ; cell division cycle 6/7/45 ; CDK1/2/4/6/7 ; cyclin-dependent kinase 1/2/4/6/7 ; CDT1 ; chromatin licensing and DNA replication factor 1 ; CFSs ; common fragile sites ; CHK1/2 ; checkpoint kinase 1/2 ; CMG ; CDC45-MCM-GINS ; CTIP ; CTBP-interacti

刊名：DNA Repair

出版年：2017

3.Senescence as biologic endpoint following pharmacological targeting of receptor tyrosine kinases in cancer

作者：Paola Francica ; Daniel M. Aebersold ; Michaela Medová ; ; ^{michaela.medova@dkf.unibe.ch}

关键词：ATIR ; anti-tumor immune response ; ATM ; ataxia telangiectasia mutated ; CDK ; cyclin-dependent kinase ; CGH ; comparative genomic hybridization ; CHK1 ; checkpoint kinase 1 ; CHK2 ; checkpoint kinase 2 ; DDAs ; DNA-damaging agents ; DDR ; DNA damage response ; DSBs ; double-strand breaks ; EGF ; epidermal growth factor ; EGFR ; epidermal growth factor receptor ; EPHA3 ; EPH Receptor A3 ; FGFR ; fibroblast growth factor receptor ; FOXM1 ; Forkhead box protein M1 ; GAS6 ; growth arrest-specific protein 6 ; H3K9me3 ; histone 3

刊名：Biochemical Pharmacology

出版年：2017

4.Progesterone inhibits proliferation and modulates expression of proliferation—Related genes in classical progesterone receptor-negative human BxPC3 pancreatic adenocarcinoma cells

作者：Alexey I. Goncharov^a ; Aitsana A. Maslakova^a ; Anna V. Polikarpova^a ; Elena A. Bulanova^b ; Alexandra A. Guseva^a ; Ivan A. Morozov^c ; Petr M. Rubtsov^c ; Olga V. Smirnova^a ; Tatiana A. Shchelkunova^a ; ^{Schelkunova-t@mail.ru} ; ^{smirnova_ov@mail.ru}

关键词：nPRs ; nuclear progesterone receptors ; mPRs ; membrane progesterone receptors ; PGRMC1 ; progesterone receptor membrane component 1 ; GR ; glucocorticoid receptors ; QPCR ; quantitative real-time PCR ; Kd ; the equilibrium dissociation constant ; RBA ; relative binding affinity ; MR ; mineralocorticoid receptors ; Ki67 ; marker of proliferation ; PCNA ; proliferating cell nuclear antigen ; cyclin D1 ; a cyclin-dependent kinases activator ; p21 ; a cyclin-dependent kinase inhibitor 1A ; p27 ; a cyclin-dependent kinase i

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

5.Bone marrow stromal cells promote neuroplasticity of cerebral ischemic rats via a phosphorylated CRMP2-mediated mechanism

作者：Xiang He^a ; ¹ ; Ling Jiang^a ; ¹ ; Qi-qin Dan^a ; Qiang Lv^a ; Yue Hu^a ; Jia Liu^b ; Shu-fen Wang^c ; ^{wsf66@hotmail.com} ; Ting-hua Wang^a ; ^b ; ^{tinghua_neuron@263.net}

关键词：CRMP2 ; collapsin response mediator protein 2 ; BMSCs ; bone marrow stromal cells ; MCAO ; middle cerebral artery occlusion ; SYP ; synaptophysin ; GSK3β ; glycogen synthase kinase 3 beta ; CDK5 ; cyclin-dependent kinase 5 ; mNSS ; modified neurological severity scores ; MEPs ; motor-evoked potentials ; SEPs ; somatosensory-evoked potentials ; CNTF ; ciliary neurotrophic factor ; PDGFB ; platelet derived growth factor subunit B ; TGFB1 ; transforming growth factor beta 1 ; NGF ; nerve growth factor ; BDNF ; brain-derived

刊名：Behavioural Brain Research

出版年：2017

6.CRMP1 and CRMP4 are required for proper orientation of dendrites of cerebral pyramidal neurons in the developing mouse brain

作者：Ryosuke Takaya^a ; Jun Nagai^a ; ^b ; Wenfui Piao^a ; Emi Niisato^a ; Takeru Nakabayashi^a ; Yuki Yamazaki^a ; Fumio Nakamura^c ; Naoya Yamashita^c ; Papachan Kolattukudy^d ; Yoshio Goshima^c ; Toshio Ohshima^a ; ^{ohshima@waseda.jp}

关键词：ANOVA ; analysis of variance ; CA1 ; cornu ammonis 1 ; Cdk ; cyclin dependent kinase ; CNS ; central nervous system ; CRMP ; collapsin response mediator protein ; CRMP2ki/ki ; CRMP2 knock-in ; EDTA ; ethylenediaminetetraacetic acid ; GFP ; green fluorescent protein ; GSK ; glycogen synthase kinase ; MAIs ; myelin-associated inhibitors ; O/N ; overnight ; PFA ; paraformaldehyde ; RT ; room temperature ; Sema3A ; semaphorin3A ; WT ; wild-type

刊名：Brain Research

出版年：2017

7.The good and the bad faces of STAT1 in solid tumours

作者：Katrin Meissl¹ ; Sabine Macho-Maschler¹ ; Mathias Mü ; ller ; Birgit Strobl ; ^{birgit.strobl@vetmeduni.ac.at}

关键词：BAD ; Bcl2-associated agonist of cell death ; Bcl ; B-cell lymphoma ; CD ; cluster of differentiation ; CDK ; cyclin-dependent kinase ; CTL ; cytotoxic T lymphocyte ; CUG ; cancer upregulated gene ; CXCL ; C-X-C motive ligand ; DC ; dendritic cells ; DAMP ; danger-associated molecular pattern ; DR ; death receptor ; ER ; estrogen receptor ; ERBB2/neu ; Erb-B2 receptor tyrosine Kinase 2 ; ERK ; extracellular signal-regulated kinase ; FASL ; FAS ligand ; FADD ; Fas-associated protein with death domain ; FGF ; fibroblast growth

刊名：Cytokine

出版年：2017

8.Explicit treatment of active-site waters enhances quantum mechanical/implicit solvent scoring: Inhibition of CDK2 by new pyrazolo[1,5-a]pyrimidines

作者：Michaela Hylsová ; ^a ; ¹ ; Benoit Carbain^a ; ^f ; ¹ ; Jindřich Fanfrlí ; k^b ; ¹ ; Lenka Musilová ; ^a ; Susanta Haldar^b ; ^c ; Cemal Kö ; prü ; lü ; oğlu^b ; ^c ; Haresh Ajani^b ; ^c ; Pathik S. Brahmkshatriya^b ; Radek Jorda^d ; Vladimí ; r Kry&scaron ; tof^d ; Pavel Hobza^b ; ^c ; Aude Echalier^e ; ² ; Kamil Paruch^a ; ^f ; ^{paruch@chemi.muni.cz} ; Martin Lep&scaron ; í ; k^b ; ^{lepsik@uochb.cas.cz}

关键词：Cyclin-dependent kinase 2 ; ATP-competitive type I inhibitors ; Pyrazolo[1 ; 5-a]pyrimidine ; Quantum mechanical scoring ; Protein-ligand binding ; Molecular dynamics ; Water thermodynamics ; X-ray crystal structure

刊名：European Journal of Medicinal Chemistry

出版年：2017

9.Molecular Control of Atypical Protein Kinase C: Tipping the Balance between Self-Renewal and Differentiation

作者：Michael L. Drummond ; Kenneth E. Prehoda ; ^{prehoda@uoregon.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：PKC ; protein kinase C ; aPKC ; atypical protein kinase C ; PrE ; primitive endoderm ; NB ; neuroblast ; Par ; partitioning defective ; Pros ; Prospero ; Brat ; brain tumor ; GMC ; ganglion mother cell ; Cdk2 ; cyclin-dependent kinase 2 ; HH ; hedgehog ; Ptch ; patched ; Smo ; smoothened ; BCC ; basal cell carcinomas ; LSCC ; lung squamous cell carcinoma ; HHAT ; HH acyl transferase ; JAK ; Janus kinase ; Stat ; Signal transducer and activator of transcription

刊名：Journal of Molecular Biology

出版年：2016

10.Pharmacological modulation of protein kinases as a new approach to treat addiction to cocaine and opiates

作者：Marí ; a Pilar Garcí ; a-Pardo ; Concepció ; n Roger-Sanchez ; Marta Rodrí ; guez-Arias ; Jose Miñ ; arro ; Marí ; a Asunció ; n Aguilar ; ^{asuncion.aguilar@uv.es" class="auth_mail" title="E-mail the corresponding author}

关键词：Cocaine ; Opiate ; Drug addiction ; Memory ; Intracellular signalling ; Protein kinases

刊名：European Journal of Pharmacology

出版年：2016

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