Garnet-bearing orthopyroxenites occurred as both discrete xenoliths and veinlets in peridotite xenoliths that were brought to the surface by Quaternary Pali Aike alkali basalts in southern South America. Or- thopyroxenites commonly contain Ti-rich minerals and also relict grains of olivine and clinopyroxene occurring as inclusions in secondary orthopyroxene. The secondary orthopyroxene contains high TiO2, moderate Al2O3 and low Mg# compared with orthopyroxene in garnet-bearing peridotites. It suggests that the secondary orthopyroxene formed at the expense of olivine and clinopyroxene during the metasomatism by an evolved Ti-rich melt. Compared with peridotites, the orthopyroxenites contain slightly low Co and Ni, and similar Cr and PGE, suggesting that these metals were essentially immobile during metasomatism.