The Tuwu porphyry copper deposit is located in Late Paleozoic Dananhu-Tousuquan island arc in East Tianshan Mountains, Xinjiang. The authors recognized a volcanic-plutonic complex at Tuwu that includes two cycles comprising four lithofacies. The pre-mineralization stage was formed at the late stage of the volcanic activity which resulted in propylitization. The mainmineralization stage was associated with the emplacement of the plagiogranite porphyry which produced potassic silicate alteration, chloritizationsericitization, and phyllic alteration as well as associated mineralization. The mineralization stages included three sub-stages, i.e., potassic silicate, chlorite-sericite, and phyllic alteration sub-stages.