///In this paper, through the application of certain Jilin gold-lead ore prospecting, using geological, geochemical, IP and other comprehensive methods, the authors achieved excellent geological prospecting effect. Establishment of geophysical and geochemical exploration of integrated prospecting model “three high-three low” (namely high gold, lead metal elements, high polarization rate, low resistivity, low magnetic, low density), combined with geological factors, have apparent guiding effect to discovery structural altered rock type gold polymetallic deposit (mineralization)　in the study area.