Historical and present seismic activity, geological investigation results and across-fault leveling data of Xinyi-Susong fault segment of Tan-Lu Fault Zone are analyzed in this paper. The results show that seismic risk is higher in two areas of the Xinyi-Susong fault segment, one is Xinyi-Sixian area, which may risks of Ms5.0~6.0 earthquake, and the other is Mingguang area, which may risks of Ms5.0 earthquake.