The Purang ophiolite in the Yarlung-Zangbo suture zone in Tibet is characterized by containing a large mantle peridotite massif of ca. 600 km2 in area. The mantle peridotite consists of dominant harzburgite, minor lherzolite and dunite, and contains some dikes or veins of olive clinopyroxenite, gabbro and diabase in the massif. The features of ophiolite imply a depleted mantle source, which were overlapped by fluid alteration in a subduction zone. It concludes that the Purang ophiolite formed in a MOR setting and was modified by fluids in a SSZ setting, similar to the Luobusa ophiolite in the eastern Yarlung-Zangbo suture zone.