The genetic algorithm is a self-adaptive heuristic global optimization search method based on the mechanism of biologic evolution which is adopted and developed recently. The conjugate gradient algorithm belongs to a non-heuristic global-optimization search method with the characteristics of swift convergence, easily dumping into local extreme value and severely depending on the primary estimation. This essay adopts a hybrid genetic algorithm for geophysical inversion based on the properties of the genetic algorithm and the conjugate gradient algorithm. The method has the attributes of the global-convergence of the genetic algorithm and the swift convergence of the conjugate gradient and achieved good results in practical application.