The Caledonian granites in South China are not so well developed as Yanshanian granites, and the Qinjia granite in southwest Guangxi is one of the famous Caledonian granites. The Qinjia granitoid pluton, located at the southwestern edge of Yangtze Plate, is a typical Early Paleozoic pluton. Based on the result of geochronology, the authors performed a lot of detailed work on geochemistry. The results show that the formation of Qinjia granite was probably linked with the collision between Yangtze Plate and Cathaysia Plate, and the source rocks of Qinjia granite were mainly composed of politic sandstone rocks, and some sediments with negative Ce anomalies probably entered magma source.