In the main oil and gas basins of China, water-soluble gas resources are also abundant, about 19×1012 m3 water-soluble gas resources distribute in 43 basins. It is recognized that abundant gas source, mechanical genesis of overpressure, reservoir and preservation conditions are the major factors forming this kind of gas pool. At present, some main problems occur in the exploration and development of domestic water-soluble gas reservoirs. It is proposed that more emphasis should be put on the exploration and development of water-soluble gas because it is probably one effective way to ensure Chinese gas supply in the future.