As a kind of special carbonate buildup, reef in carbonate strata was good deposited room for oil and gas. To reveal its seismic wave field response characteristics, a high-precision phase shift plus interpolation wave field continuation operator was used in the forward modeling and migration on reef model built based on geologic features of reef reservoir. The results showed that abnormal response on seismic section was consequentially induced by reef’s peculiar geologic conditions. The analysis and interpretation on response characteristics were helpful in oil and gas exploration, and seismic wave field simulation could be guidance in oil and gas exploration of reef reservoirs.