Taking manganese deposits in western Guangxi and southeastern Yunnan of China as an example, the prediction and assessment database for mineral resources is introduced in detail. Based on analysis of characteristics of geological data, such as multi-source, distribution, multi-scale and legacy, the global architecture of mineral resources prediction and assessment database is proposed finally. By the application of manganese ore prediction and assessment in western Guangxi and southeastern Yunnan of China, the heterogeneous databases based on same data service interface and the hybrid database system architecture of browser/server and client/server are proposed, which supply uniform and standardized data platform support for the studies of metallogenetic regularities, prospecting model and synthesized assessment of mineral resources based on GIS.