In this paper, the heterogeneity synthetic index (HSI) was introduced to characterize  synthetic heterogeneity of aquifer. This approach was applied to Luancheng aquifer deposit in the southeast Hutuo River alluvial-pluvial fan in the North China Plain (NCP).The results indicated that the heterogeneity was weak in the radial direction of alluvial-pluvial fan due to the micro-facies changed mildly and the continuity of hydrogeology parameter was better, the HSI was 0.74~0.95; while in the superstition zone of alluvial-pluvial fan, the heterogeneity of aquifer was stronger, HSI was 0.38~0.65. The sedimentary environment had significant effect on heterogeneity of aquifer.