In Qimantage area of the East Kunlun region, Xinjiang many ore deposits minor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">(occurrencesminor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">) which are dominated by Fe, Pb, Zn, Cu, Au, W, and Sn repectively have been discovered. According to region- al geological and metallogical condition, regional geochemical characteristics of Weibao area and Pb-Zn ore-hosted strata and occurrence and mineralization characteristics, wall rock alteration and ore material source of the Pb-Zn deposits in Weibao area the area possesses geological and geochemical conditions by which large Pb-Zn deposits could be formed thus is potential for further exploration of the deposits. Pros- pecting marks are summarized and empirical prospecting model is built. Pb-zn ore prospecting orientations are pointed out and prospecting targets located and suggestions for exploration of different deposits put forward.