Natural pyrethrins induces apoptosis in human hepatocyte cells via Bax- and Bcl-2-mediated mitochondrial pathway

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• 作者：Yun Yang ; Mimi Zong ; Wenping Xu ; Yang Zhang ; Bo Wang ; Mingjun Yang ; Liming Tao ; ^{taolm@ecust.edu.cn}
• 关键词：Natural pyrethrins ; Cytotoxic effects ; Human hepatocyte cells ; Apoptosis ; The mitochondrial pathway
• 刊名：Chemico-Biological Interactions
• 出版年：2017
• 出版时间：25 January 2017
• 年：2017
• 卷：262
• 期：Complete
• 页码：38-45
• 全文大小：1891 K
• 卷排序：262

文摘

Natural pyrethrins has potential threats to human health. Natural pyrethrins has significant cytotoxicity to Human hepatocyte cells in vitro. Natural pyrethrins induces caspase-dependent apoptosis in HepG2 cells through Bax- and Bcl-2-triggered mitochondrial pathway.