Hippocampal atrophy on MRI is predictive of histopathological patterns and surgical prognosis in mesial temporal lobe epilepsy with hippocampal sclerosis

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• 作者：Anaclara Prada Jardim<sup>asup><sup> ; sup><sup>anaclarapjardim@gmail.comsup><sup> ; sup><sup>aninhapj@uol.com.brsup> ; Jeana Torres Corso<sup>asup> ; Maria Teresa Fernandes Castilho Garcia<sup>asup> ; Larissa Botelho Gaç ; a<sup>asup> ; Sandra Mara Comper<sup>asup> ; Carmen Lú ; cia Penteado Lancellotti<sup>bsup> ; Ricardo Silva Centeno<sup>csup> ; Henrique Carrete Jú ; nior<sup>dsup> ; Esper Abrã ; o Cavalheiro<sup>esup> ; Carla Alessandra Scorza<sup>esup> ; Elza Má ; rcia Targas Yacubian<sup>asup>
• 关键词：Mesial temporal lobe epilepsy ; Hippocampal sclerosis ; Hippocampal atrophy ; Surgical outcome ; FreeSurfer analysis
• 刊名：Epilepsy Research
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：128
• 期：Complete
• 页码：169-175
• 全文大小：1533 K
• 卷排序：128

文摘

Hippocampal volumes are predictive of hippocampal sclerosis patterns. Hippocampi is smaller in types 1 and 2, intermediate in 3 and higher in no-HS. Neuronal densities of CA1, CA3 and CA4 subfields influence hippocampal volume. CA2 subfield neuronal density does not correlate with hippocampal imaging volume. Surgical prognosis is better in type 1 HS, intermediate in 2&ndash;3 and worse in no-HS.