NMDAR antagonists blocks depotentiation of stabilized hippocampal E-LTP and L-LTP.

Chronic post-acquisition blockade of NMDAR protects LTMs from its active decay.

Endocytosis of GluA2-containing AMPAR is one of the main signatures underlying forgetting.

Decay of the L-LTP or LTM might rely on spine shrinkage through LIMK/cofilin-mediated signalling.

Ubiquitin-proteasome system may regulate both memory destabilization and forgetting.