Advances in hydrotropic solutions: An updated review

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• 作者：Vividha Dhapte ; ^{vividhapte@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; ^{vividhadhapte@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Piyush Mehta ^{piyu053@gmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Hydrotropy ; Mesoscale solubilization ; Drug carriers and Green chemistry
• 刊名：St. Petersburg Polytechnical University Journal: Physics and Mathematics
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：1
• 期：4
• 页码：424-435
• 全文大小：1045 K

文摘

Approximately a century ago, in 1916, the term ‘hydrotropy’ was coined by the scientist Carl A. Neuberg to address anionic organic salts which considerably augmented the aqueous solubility of poorly soluble solutes. Currently hydrotropic solutions possess high industrial demand due to their unique features such as easy availability, good recovery, absence of fire hazards, higher separation factors without any solutes emulsification problem and eco-friendly nature. The present review takes the readers through a concise overview, geometrical features of hydrotropic agents, hypothetical mechanisms and their different advances toward drug delivery. Moreover, this review would provide an insight of the future perspectives concerned with the drug delivery and hydrotropism.