Assessing the potential for interaction between the insecticidal activity of two genetically engineered cotton events combined by conventional breeding: An example with COT102 × MON 15985
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- 作者：Steven L. Levine ; steven.l.levine@monsanto.com" class="auth_mail" title="E-mail the corresponding author ; Geoffrey M. Mueller ; Joshua P. Uffman
- 关键词：Bt protein ; Plant incorporated protectants ; Cotton ; Cry1Ac ; Cry2Ab2 ; Vip3Aa19 ; Additivity ; Concentration addition
- 刊名：Regulatory Toxicology and Pharmacology
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：79
- 期：Complete
- 页码：35-41
- 全文大小：416 K
文摘
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Bollgard III was developed by combining cotton events COT102 and MON15985.
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MON15985 produces Cry1Ac & Cry2Ab2 proteins and COT102 produces the Vip3Aa19 protein.
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Activity of insecticidal activity was additive.
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Additivity is consistent with competition & ligand assays showing independent binding.