Effect of protein S-nitrosylation on autolysis and catalytic ability of μ-calpain
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- 作者：Rui Liu1 ; Yupin Li1 ; Mengqin Wang ; Guanghong Zhou ; Wangang Zhang ; wangang.zhang@njau.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：μ-Calpain ; Autolysis and proteolysis ; Nitric oxide ; Protein S-nitrosylation ; Myofibril degradation
- 刊名：Food Chemistry
- 出版年：2016
- 出版时间：15 December 2016
- 年：2016
- 卷：213
- 期：Complete
- 页码：470-477
- 全文大小：1148 K
文摘
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Autolysis of μ-calpain was inhibited after GSNO treatment.
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Proteolytic degradation of myofibril by S-nitrosylated μ-calpain was reduced.
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The inhibitory effect of GSNO on μ-calpain seemed dose-dependent.
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S-nitrosylated peptides and cysteines of μ-calpain were identified.