Hepatoprotection using Brassica rapa var. rapa L. seeds and its bioactive compound, sinapine thiocyanate, for CCl4-induced liver injury
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- 作者：Rao Fu1 ; Yuting Zhang1 ; Yiran Guo ran@scu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Tong Peng ; Fang Chen ; fangchen1112@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：AAPH ; 2 ; 2'-azobis(2-amidinopropane) ; ALP ; alkaline phosphatase ; ALT ; alanine aminotransferase ; ANOVA ; one-way analysis of variance ; AST ; aspartate aminotransferase ; AUC ; area under curve ; CCl4 ; carbon tetrachloride ; DDB ; biphenyldicarboxylate ; DPPH ; 2 ; 2-diphenyl-1-picrylhydrazyl ; EE ; absolute ethanol extract ; GAE ; gallic acid equivalents ; H&E ; haematoxylin and eosin ; HEE ; 50% ethanol extract ; MDA ; malondialdehyde ; ORAC ; oxygen radical absorbance capacity ; PDA ; photodiode array detector ; ROS ; rea
- 刊名：Journal of Functional Foods
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：22
- 期：Complete
- 页码：73-81
- 全文大小：1357 K
文摘
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Three extracts were prepared according to the traditional use method of B. rapa.
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All extracts exhibited strong antioxidant activities and hepatoprotective effects.
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Sinapine thiocyanate was the main compound of all extracts.
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Hepatoprotective effect of sinapine thiocyanate was verified.
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Provided the modern scientific evidence for the traditional use of B. rapa seeds.