The blood-brain barrier in systemic inflammation

详细信息    查看全文

• 作者：Aravinthan Varatharaj ; ^{a.varatharaj@soton.ac.uk} ; Ian Galea ^{i.galea@soton.ac.uk}
• 关键词：Blood-brain barrier ; Systemic inflammation ; Lipopolysaccharide ; Sickness behaviour ; Delirium ; Septic encephalopathy ; Multiple sclerosis ; Alzheimer&rsquo ; s disease
• 刊名：Brain, Behavior, and Immunity
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：60
• 期：Complete
• 页码：1-12
• 全文大小：1069 K
• 卷排序：60

文摘

Systemic inflammation may cause changes in the blood-brain barrier (BBB). These changes may be disruptive or non-disruptive. BBB changes may protect the central nervous system, or may induce disease. In neurological disease, the BBB may be more vulnerable to systemic inflammation.