Inorganic mesoporous silicas as vehicles of two novel anthracene-based ruthenium metalloarenes

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• 作者：Sara Rojas ; Francisco J. Carmona ; Elisa Barea ; ^{ebaream@ugr.es} ; Carmen R. Maldonado ; ^{crmaldonado@ugr.es}
• 关键词：Ruthenium metallodrug ; Fluorescence ; MCM-41 ; SBA-15 ; Cathepsin inhibition ; Drug encapsulation
• 刊名：Journal of Inorganic Biochemistry
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：166
• 期：Complete
• 页码：87-93
• 全文大小：497 K
• 卷排序：166

文摘

Two novel anthracene-based ruthenium metallodrugs have been designed. The complexes exhibit interaction with biological targets and moderate cytotoxicity. The encapsulation of the metallodrugs into mesoporous silicas has been achieved.