A novel lutetium(III) acetate phthalocyanine directly substituted with N,N’-dimethylaminophenyl groups via CC bonds and its water-soluble derivative for photodynamic therapy

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• 作者：Shaya Y. Al-Raqa^a ; Baybars Kö ; ksoy^b ; Mahmut Durmuş^b ; ^{durmus@gtu.edu.tr}
• 关键词：Phthalocyanine ; Suzuki-coupling ; Lutetium ; Water soluble ; PDT
• 刊名：Tetrahedron Letters
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：58
• 期：7
• 页码：685-689
• 全文大小：963 K
• 卷排序：58

文摘

Synthesis of a N,N′-dimethylaminophenyl substituted lutetium(III) phthalocyanine. Synthesis of a quaternized, water soluble lutetium(III) phthalocyanine. Photochemical properties of the phthalocyanines in both DMSO and water. High singlet oxygen generation for potential photodynamic therapy of cancer.