Baseline oxygenation in the brain: Correlation between respiratory-calibration and susceptibility methods
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- 作者：Audrey P. Fana ; b ; 1 ; auddie@stanford.edu" class="auth_mail" title="E-mail the corresponding author ; Andreas Schä ; fera ; schaefer@cbs.mpg.de" class="auth_mail" title="E-mail the corresponding author ; Laurentius Hubera ; lhuber@cbs.mpg.de" class="auth_mail" title="E-mail the corresponding author ; Leonie Lampea ; lampe@cbs.mpg.de" class="auth_mail" title="E-mail the corresponding author ; Steffen von Smudaa ; steffen.von.smuda@cbs.mpg.de" class="auth_mail" title="E-mail the corresponding author ; Harald E. Mö ; llera ; moeller@cbs.mpg.de" class="auth_mail" title="E-mail the corresponding author ; Arno Villringera ; villringer@cbs.mpg.de" class="auth_mail" title="E-mail the corresponding author ; Claudine J. Gauthiera ; c ; claudine.gauthier@concordia.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：ANOVA ; analysis of variance ; ASL ; arterial spin labeling ; BOLD ; blood oxygenation level dependent ; CBF ; cerebral blood flow ; CMRO2 ; cerebral metabolic rate of oxygen ; BOLD ; blood oxygenation level dependent ; dHb ; deoxyhemoglobin ; ETO2 ; end-tidal O2 ; GCM ; generalized calibration model ; Hct ; hematocrit ; OEF ; oxygen extraction fraction ; QSM ; quantitative susceptibility mapping ; QUO2 ; quantitative oxygenation imaging ; ROI ; region of interest ; SNR ; signal-to-noise ratio ; TV ; total variation
- 刊名：NeuroImage
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：125
- 期：Complete
- 页码：920-931
- 全文大小：1096 K
文摘
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We compared two MRI methods to image oxygen extraction fraction (OEF): QUO2 and quantitative susceptibility mapping (QSM).
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OEF values from QUO2 with three gas challenges correlated with OEF values from QSM in cerebral veins.
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QUO2 measurements of OEF depend on accurate measurement of the hyperoxic BOLD signal.
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Blood flow changes during visual stimulation correlated with baseline OEF by both methods.