Foundations of MRI phase imaging and processing for Quantitative Susceptibility Mapping (QSM)

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• 作者：Ferdinand Schweser^a ; ^b ; ^{mail@ferdinand-schweser.de" class="auth_mail" title="E-mail the corresponding author} ; Andreas Deistung^c ; Jü ; rgen R. Reichenbach^c ; ^d
• 关键词：MRI phase ; magnetic susceptibility ; QSM ; phase processing
• 刊名：Zeitschrift für Medizinische Physik
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：26
• 期：1
• 页码：6-34
• 全文大小：1709 K

文摘

Quantitative Susceptibility Mapping (QSM) is a novel MRI based technique that relies on estimates of the magnetic field distribution in the tissue under examination. Several sophisticated data processing steps are required to extract the magnetic field distribution from raw MRI phase measurements. The objective of this review article is to provide a general overview and to discuss several underlying assumptions and limitations of the pre-processing steps that need to be applied to MRI phase data before the final field-to-source inversion can be performed. Beginning with the fundamental relation between MRI signal and tissue magnetic susceptibility this review covers the reconstruction of magnetic field maps from multi-channel phase images, background field correction, and provides an overview of state of the art QSM solution strategies.