High-resolution characterisation of the aging brain using simultaneous quantitative susceptibility mapping (QSM) and R2* measurements at 7 T
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- 作者：Matthew J. Bettsa ; 1 ; matthew.betts@dzne.de" class="auth_mail" title="E-mail the corresponding author ; Julio Acosta-Cabroneroa ; 1 ; Arturo Cardenas-Blancoa ; b ; Peter J. Nestora ; Emrah Dü ; zela ; b ; c
- 关键词：Brain iron ; Brain mineralisation ; Aging ; Quantitative susceptibility mapping ; R2* mapping ; Cortex ; Subcortical grey matter ; White matter
- 刊名：NeuroImage
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：138
- 期：Complete
- 页码：43-63
- 全文大小：6210 K
文摘
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Combined absolute QSM, signed QSM and R2* proposed to study age-related mineralisation.
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Absolute QSM and R2* detected age-related differences in the basal ganglia and cortex.
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R2* but not QSM showed age-related differences in the pallidum and occipital cortex.
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QSM revealed greater age-related differences than R2* in the thalamus and white matter.