Association between Feeding Difficulties and Language Delay in Preterm Infants Using Bayley Scales of Infant Development-Third Edition

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• 作者：Ira Adams-Chapman ; Carla M. Bann ; Yvonne E. Vaucher ; Barbara J. Stoll ; Eunice Kennedy Shriver National Institute of Child Health ; Human Development (NICHD) Neonatal Research Network (NRN)
• 关键词：BSID-III ; Bayley Scales of Infant Development-Third Edition ; ELBW ; Extremely low birth weight ; GMFCS ; Gross Motor Functional Classification System ; IVH ; Intraventricular hemorrhage ; MRI ; Magnetic resonance imaging ; ND ; Neurodevelopmental ; NEC ; Necrotizing
• 刊名：The Journal of Pediatrics
• 出版年：2013
• 出版时间：September, 2013
• 年：2013
• 卷：163
• 期：3
• 页码：680-685.e3
• 全文大小：147 K

文摘

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Objective

To evaluate the relationship between abnormal feeding patterns and language performance on the Bayley Scales of Infant Development-Third Edition at 18-22 months adjusted age among a cohort of extremely premature infants.

Study design

This is a descriptive analysis of 1477 preterm infants born ¡Ü26 weeks gestation or enrolled in a clinical trial between January 1, 2006 and March 18, 2008 at a National Institute of Child Health and Human Development Neonatal Research Network center who completed the 18-month neurodevelopmental follow-up assessment. At 18-22 months adjusted age, a comprehensive neurodevelopmental evaluation was performed by certified examiners including the Receptive and Expressive Language Subscales of the Bayley Scales of Infant Development-Third Edition and a standardized adjusted age feeding behaviors and nutritional intake. Data were analyzed using bivariate and multilevel linear and logistic regression modeling.

Results

Abnormal feeding behaviors were reported in 193 (13 % ) of these infants at 18-22 months adjusted age. Abnormal feeding patterns, days of mechanical ventilation, hearing impairment, and Gross Motor Functional Classification System level ¡Ý2 each independently predicted lower composite language scores.

Conclusions

At 18 months adjusted age, premature infants with a history of feeding difficulties are more likely to have language delay. Neuromotor impairment and days of mechanical ventilation are both important risk factors associated with these outcomes.