Effect of molecular weight and concentration of hyaluronan on cell proliferation and osteogenic differentiation in聽vitro
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- 作者：Ningbo Zhao curl-zhao@163.com" class="auth_mail" title="E-mail the corresponding author ; Xin Wang 394041230@qq.com" class="auth_mail" title="E-mail the corresponding author ; Lei Qin qinlei30@126.com" class="auth_mail" title="E-mail the corresponding author ; Zhengze Guo zhzeguo@163.com" class="auth_mail" title="E-mail the corresponding author ; Dehua Li ; lidehuafmmu@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hyaluronan ; Molecular weight ; Concentration ; Proliferation ; Differentiation
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2015
- 出版时间：25 September 2015
- 年：2015
- 卷：465
- 期：3
- 页码：569-574
- 全文大小：1415 K
文摘
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Effect of hyaluronan on cell proliferation and differentiation is evaluated in vitro.
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Hyaluronan of low molecular weight increases cell proliferation.
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Hyaluronan of high molecular weight promotes cell osteogenic differentiation.
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Molecular weight and concentration of hyaluronan show interactive effect.