Murine breast carcinoma 4T1 cells are more sensitive to atranorin than normal epithelial NMuMG cells in vitro: Anticancer and hepatoprotective effects of atranorin in vivo
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- 作者：Peter Solá ; r<sup>asup><sup> ; sup><sup>peter.solar@upjs.sk" class="auth_mail" title="E-mail the corresponding authorsup> ; Gabriela Hrčková ; <sup>bsup> ; Lenka Kopta&scaron ; í ; ková ; <sup>asup> ; Samuel Velebný ; <sup>bsup> ; Zuzana Solá ; rová ; <sup>csup> ; Martin Bačkor<sup>asup>
- 关键词：Lichen ; Atranorin ; 4T1 breast cancer ; NMuMG cells ; BALB/c mouse ; Lipid peroxidation
- 刊名：Chemico-Biological Interactions
- 出版年：2016
- 出版时间：25 April 2016
- 年：2016
- 卷：250
- 期：Complete
- 页码：27-37
- 全文大小：2381 K
文摘
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Atranorin induces apoptosis of mouse mammary carcinoma 4T1 cells in vitro and in vivo.
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Normal mammary epithelial NMuMG cells are less sensitive to atranorin than carcinoma 4T1 cells.
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Atranorin protects against lipid peroxidation in liver cells of in vivo mouse mammary carcinoma model.