Superparamagnetic-Oil-Filled Nanocapsules of a Ternary Graft Copolymer

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• 作者：Lei Miao ; Feng Liu ; Shudong Lin ; Jiwen Hu ; Guojun Liu ; Yang Yang ; Yuanyuan Tu ; Chengmin Hou ; Fei Li ; Meilong Hu ; Hongsheng Luo
• 刊名：Langmuir
• 出版年：2014
• 出版时间：April 15, 2014
• 年：2014
• 卷：30
• 期：14
• 页码：3996-4004
• 全文大小：480K
• 年卷期：v.30,no.14(April 15, 2014)
• ISSN：1520-5827

文摘

Stearic and oleic acid-coated Fe₃O₄ nanoparticles were dispersed in decahydronaphthalene (DN). This oil phase was dispersed in water using ternary graft copolymer poly(glycidyl methacrylate)-graft-[polystyrene-ran-(methoxy polyethylene glycol)-ran-poly(2-cinnamoyloxyethyl methacrylate)] or PGMA-g-(PS-r-MPEG-r-PCEMA) to yield capsules. The walls of these capsules were composed of PCEMA chains that were soluble in neither water nor DN, and the DN-soluble PS chains stretched into the droplet phase and the water-soluble MPEG chains extended into the aqueous phase. Structurally stable capsules were prepared by photolyzing the capsules with UV light to cross-link the PCEMA layer. Both the magnetite particles and the magnetite-containing capsules were superparamagnetic. The sizes of the capsules increased as they were loaded with more magnetite nanoparticles, reaching a maximal loading of 0.5 mg of ligated magnetite nanoparticles per mg of copolymer. But the radii of the capsules were always <100 nm. Thus, a novel nanomaterial鈥攕uperparamagnetic-oil-filled polymer nanocapsules鈥攚as prepared. The more heavily loaded capsules were readily captured by a magnet and could be redispersed via shaking. Although the cross-linked capsules survived this capturing and redispersing treatment many times, the un-cross-linked capsules ruptured after four cycles. These results suggest the potential to tailor-make capsules with tunable wall stability for magnetically controlled release applications.