2,5-Oxyarylation of Furans: Synthesis of Spiroacetals via Palladium-Catalyzed Aerobic Oxidative Coupling of Boronic Acids with α-Hydroxyalkylfurans

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• 作者：Jiuyi Li ; Hui Peng ; Furong Wang ; Xiujun Wang ; Huanfeng Jiang ; Biaolin Yin
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：July 1, 2016
• 年：2016
• 卷：18
• 期：13
• 页码：3226-3229
• 全文大小：358K
• 年卷期：0
• ISSN：1523-7052

文摘

A protocol for the 2,5-oxyarylation of furan rings via Pd-catalyzed aerobic oxidative coupling of boronic acids with α-hydroxyalkylfurans is reported. This protocol provides rapid, green access to diverse biologically interesting and synthetically useful unsaturated spiroacetals from sustainable furan derivatives.