Stictic Acid Derivatives from the Lichen Usnea articulata and Their Antioxidant Activities
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- 作者：Franç ; oise Lohé ; zic-Le Dé ; vé ; hat ; Sophie Tomasi ; John A. Elix ; Auré ; lie Bernard ; Isabelle Rouaud ; Philippe Uriac ; Joë ; l Boustie
- 刊名：Journal of Natural Products
- 出版年：2007
- 出版时间：July 2007
- 年：2007
- 卷：70
- 期：7
- 页码：1218 - 1220
- 全文大小：47K
- 年卷期：v.70,no.7(July 2007)
- ISSN：1520-6025
文摘
Two new 
-orcinol depsidones, 1 and 2, together with 13 known compounds were isolated from the lichen Usneaarticulata. The structures of 1 and 2 were elucidated by spectroscopic analyses and those of known compounds bycomparison of their spectroscopic data with literature values or by direct comparison with authentic standards. Compounds1, 2, and 5 exhibited moderate antiradical activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The depsidones4 and 5 showed better superoxide anion scavenging activity (IC50 = 566 and 580 
M, respectively) than quercetin(IC50 = 754 M).
-orcinol depsidones, 1 and 2, together with 13 known compounds were isolated from the lichen Usneaarticulata. The structures of 1 and 2 were elucidated by spectroscopic analyses and those of known compounds bycomparison of their spectroscopic data with literature values or by direct comparison with authentic standards. Compounds1, 2, and 5 exhibited moderate antiradical activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The depsidones4 and 5 showed better superoxide anion scavenging activity (IC50 = 566 and 580 M, respectively) than quercetin(IC50 = 754 M).