FeCl3-Mediated Radical Tandem Reactions of 3-Benzyl-2-oxindoles with Styrene Derivatives for the Stereoselective Synthesis of Spirocyclohexene Oxindoles

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• 作者：Hong-Ru Wu ; Liang Cheng ; De-Long Kong ; Hong-Yan Huang ; Chun-Ling Gu ; Li Liu ; Dong Wang ; Chao-Jun Li
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：March 18, 2016
• 年：2016
• 卷：18
• 期：6
• 页码：1382-1385
• 全文大小：401K
• ISSN：1523-7052

文摘

A novel FeCl₃-mediated reaction of 3-benzyl-2-oxindoles with styrene derivatives was developed. The reaction provided spirocyclohexene oxindoles in good yields and excellent diastereoselectivities via a tandem radical addition/cyclization process.