Interligand Interactions Controlling the -N7,N9-Metal Bonding of Adenine (AdeH) to the N-Benzyliminodiacetato(2-) Copper(II) Ch
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- 作者：Perla X. Rojas-Gonzá ; lez ; Alfonso Castiñ ; eiras ; Josefa M. Gonzá ; lez-Pé ; rez ; Duane Choquesillo-Lazarte ; and Juan Nicló ; s-Gutié ; rrez
- 刊名：Inorganic Chemistry
- 出版年：2002
- 出版时间：December 2, 2002
- 年：2002
- 卷：41
- 期：24
- 页码：6190 - 6192
- 全文大小：64K
- 年卷期：v.41,no.24(December 2, 2002)
- ISSN：1520-510X
文摘
The reaction in water of the N-benzyliminodiacetate-copper(II)chelate ([Cu(NBzIDA)]) and the adenine:thymine base pair complex(AdeH:ThyH) with a Cu/NBzIDA/AdeH/ThyH molar ratio of 2:2:1:1yields [Cu2(NBzIDA)2(H2O)2(
-N7,N9-Ade(N3)H)]·3H2O and freeThyH. The compound has been studied by thermal, spectral, andX-ray diffraction methods. In the asymmetric dinuclear complexunits both Cu(II) atoms exhibit a square pyramidal coordination,where the four closest donors are supplied by NBzIDA in a mer-tridentate conformation and the N7 or N9 donors of AdeH, whichis protonated at N3. The -N7,N9 bridge represents a newcoordination mode for nonsubstituted AdeH, except for someadeninate(1-)-[methylmercury(II)] derivatives studied earlier. Thedinuclear complex is stabilized by the Cu-N7 and Cu-N9 bondsand N6-H(exocyclic)···O(carboxyl) and N3-H(heterocyclic)···O(carboxyl) interligand interactions, respectively. The structure ofthe new compound differs from that of the mononuclear compound[Cu(NBzIDA)(Ade(N9)H)(H2O)]·H2O, in which the unusual Cu-N3(AdeH) bond is stabilized by a N9-H···O(carboxyl) interligandinteraction and where alternating benzyl-AdeH intermolecular 
,-stacking interactions produce infinite stacked chains. The possibilityfor ThyH to be involved in the molecular recognition between [Cu(NBzIDA)] and the AdeH:ThyH base pair is proposed.
-N7,N9-Ade(N3)H)]·3H2O and freeThyH. The compound has been studied by thermal, spectral, andX-ray diffraction methods. In the asymmetric dinuclear complexunits both Cu(II) atoms exhibit a square pyramidal coordination,where the four closest donors are supplied by NBzIDA in a mer-tridentate conformation and the N7 or N9 donors of AdeH, whichis protonated at N3. The -N7,N9 bridge represents a newcoordination mode for nonsubstituted AdeH, except for someadeninate(1-)-[methylmercury(II)] derivatives studied earlier. Thedinuclear complex is stabilized by the Cu-N7 and Cu-N9 bondsand N6-H(exocyclic)···O(carboxyl) and N3-H(heterocyclic)···O(carboxyl) interligand interactions, respectively. The structure ofthe new compound differs from that of the mononuclear compound[Cu(NBzIDA)(Ade(N9)H)(H2O)]·H2O, in which the unusual Cu-N3(AdeH) bond is stabilized by a N9-H···O(carboxyl) interligandinteraction and where alternating benzyl-AdeH intermolecular ,-stacking interactions produce infinite stacked chains. The possibilityfor ThyH to be involved in the molecular recognition between [Cu(NBzIDA)] and the AdeH:ThyH base pair is proposed.