Copper-Catalyzed Cross-Dehydrogenative C鈥揘 Bond Formation of Azines with Azoles: Overcoming the Limitation of Oxidizing N鈥揙 Activation Strategy
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- 作者：Kai Sun ; Xin Wang ; Lulu Liu ; Jingjing Sun ; Xin Liu ; Zhenduo Li ; Zhiguo Zhang ; Guisheng Zhang
- 刊名：ACS Catalysis
- 出版年：2015
- 出版时间：December 4, 2015
- 年：2015
- 卷：5
- 期：12
- 页码：7194-7198
- 全文大小：448K
- ISSN：2155-5435
文摘
Here, we report the copper-catalyzed C2 selective cross-dehydrogenative C鈥揘 bond formation of azines with azoles. This straightforward method enables us to address the key limitation of prior N鈥揙 activation strategy in C2 amination of azines. The wide substrate scope, high functional group tolerance, and ease of operation of the present method are expected to promote its potential application in synthetic chemistry.